IP Library › Granted Patent US 12,419,910
Granted Patent B2
US 12,419,910 · App. 17/842,100 · Granted Sep 23, 2025

Acetic acid and hypochlorous acid compositions for treatment of skin trauma

Inventor: Geir Hermod Almås (Snarøya, NO)
Assignee: WIAB WATER INNOVATION AB
A61K33/20A61K9/0014A61K31/19A61K33/42C01B11/04A61K2300/00
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Quick Facts
Patent No.
US 12,419,910
App. No.
17/842,100
Granted
Sep 23, 2025
Kind
B2
Abstract

Disinfecting compositions containing hypochlorous acid and acetic acid are useful for treating biofilms in or on tissue, including biofilms related to wounds or other skin trauma. The compositions are useful for treating a variety of types of tissue, both on the surface on beneath the surface of tissue. Compositions are provided having various concentrations for different tissue types and infection levels. Compositions may be provided in gel form, and may include nanoparticle encapsulated molecules for controlled release.

Claims (22)

1. A method for treating tissue trauma, the method comprising:

providing to a tissue subject to trauma a composition comprising:

an aqueous solution;

hypochlorous acid (HOC1) at an HOC1 concentration between about 10 and 500 ppm in the aqueous solution; and

acetic acid (HAc) at an HAc concentration between about 0.25% and 5.0%, wherein the HAc is encapsulated in a nanoparticle contained in the aqueous solution.

2. The method of claim 1 , wherein the tissue is within a surgical operating field.

3. The method of claim 1 , wherein the composition is provided to the tissue before making a surgical incision.

4. The method of claim 1 , wherein the composition is provided to the tissue after making a surgical incision.

5. The method of claim 1 , further comprising debriding the tissue with the composition.

6. The method of claim 1 , wherein the tissue comprises skin.

7. The method of claim 1 , wherein the hypochlorous acid concentration is approximately 200 ppm.

8. The method of claim 1 , wherein the composition is buffered and has a pH approximately equal to a pKa of acetic acid.

9. The method of claim 1 , wherein the composition comprises a liquid, powder, lotion, cream, gel, oil, ointment, solid, semi-solid, or aerosol spray.

10. The method of claim 1 , wherein providing comprises spraying a mist onto the tissue, contacting the tissue with a wipe comprising the composition, contacting the tissue with a cream or lotion comprising the composition, soaking the tissue in the composition, submerging the tissue in the composition, or washing the tissue with the composition.

11. A method for treating a biofilm in a wound, the method comprising providing to the wound a composition comprising hypochlorous acid (HOC1) at an HOC1 concentration between about 10 and 500 ppm and acetic acid (HAc) at an HAc concentration between about 0.25% and 5.0%, wherein the HAc is encapsulated in a nanoparticle.

12. The method of claim 11 , wherein the wound comprises a bedsore, a chronic wound, a burn, a pressure wound, a diabetes-related wound, or a surgical site.

13. The method of claim 11 , further comprising debriding the wound with the composition.

14. The method of claim 11 , wherein the composition is substantially free of chlorine gas.

15. The method of claim 11 , wherein the composition is buffered.

16. The method of claim 11 , wherein the composition is buffered and has a pH approximately equal to a pKa of acetic acid.

17. The method of claim 11 , wherein the composition comprises a liquid, powder, lotion, cream, gel, oil, ointment, solid, semi-solid, or aerosol spray.

18. The method of claim 11 , wherein providing comprises spraying a mist onto the tissue, contacting the tissue with a wipe comprising the composition, contacting the tissue with a cream or lotion comprising the composition, soaking the tissue in the composition, submerging the tissue in the composition, or washing the tissue with the composition.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 28, 2023
From: ALMAS, GEIR HERMOD
To: WIAB WATER INNOVATION AB
Reel/Frame 063475/0001 →
Continuity (14)
Continuation 15852603 · Dec 22, 2017
Continuation In Part 15612571 · Jun 2, 2017
Continuation In Part 15267220 · Sep 16, 2016
Continuation 15167076 · May 27, 2016
Continuation In Part 14618820 · Feb 10, 2015
Continuation In Part 14618799 · Feb 10, 2015
Continuation In Part 13770738 · Feb 19, 2013
Continuation 13770738 · Feb 19, 2013
Provisional Application 62438198 · Dec 22, 2016
Provisional Application 62438204 · Dec 22, 2016
Provisional Application 62438189 · Dec 22, 2016
Provisional Application 62438202 · Dec 22, 2016
Provisional Application 61600344 · Feb 17, 2012
Related Publication 20220387484A1 · Dec 8, 2022
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