IP Library Granted Patent US 12,422,360
Granted Patent B2
US 12,422,360 · App. 17/447,994 · Granted Sep 23, 2025

Apparatuses, systems, and methods for sample testing

Inventors: Chen Feng (Mount Laurel, NJ); Moin Shafai (Plano, TX); Suresh Venkatarayalu (Waxhaw, NC)
Assignee: Hand Held Products, Inc.
G01N21/45B23D63/008C23C2/51G02B6/4204A61H2201/5007B01D2313/70B01D2313/701B29C2037/903C02F2209/006G01N2021/4166G01N2201/0846
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Quick Facts
Patent No.
US 12,422,360
App. No.
17/447,994
Granted
Sep 23, 2025
Kind
B2
Abstract

Methods, apparatuses, and systems associated with a sample testing device are provided. For example, an example sample testing device may include a substrate layer defining a bottom surface of the sample testing device, as well as a waveguide disposed on the substrate layer and includes at least one reference channel and at least one sample channel.

Claims (35)

1. A sample sensing device comprising:

a waveguide holder component, wherein a first surface of the waveguide holder component comprises at least one alignment feature;

a waveguide component comprising at least one etched edge; and

wherein the at least one alignment feature comprises at least one protrusion on the first surface of the waveguide holder component, wherein the at least one protrusion is configured to align the waveguide component to allow media to flow through a plurality of flow channels within the waveguide component, wherein, when in an alignment arrangement, the at least one etched edge of the waveguide component is configured to be in contact with the at least one protrusion of the at least one alignment feature of the waveguide holder component.

2. The sample sensing device of claim 1 , wherein the waveguide holder component comprises:

a holder cover element; and

a fluid gasket element secured to the holder cover element, wherein the fluid gasket element is positioned between the holder cover element and the waveguide component.

3. The sample sensing device of claim 2 , wherein the holder cover element comprises a plurality of input openings on a top surface of the holder cover element, wherein the fluid gasket element comprises a plurality of input channels protruding from a top surface of the fluid gasket element.

4. The sample sensing device of claim 1 , wherein the sample sensing device further comprises:

a thermal pad component disposed on a bottom surface of the waveguide component.

5. The sample sensing device of claim 1 , wherein the waveguide component comprises:

a plurality of optical channels within the waveguide component, wherein each of the plurality of optical channels defines an optical path.

6. The sample sensing device of claim 5 , wherein the waveguide component comprises:

an input edge comprising a plurality of input openings, wherein each of the plurality of input openings corresponds to one of the plurality of optical channels.

7. The sample sensing device of claim 6 , wherein the input edge is configured to receive light.

8. The sample sensing device of claim 6 , wherein each of the plurality of input openings is configured to receive light.

9. The sample sensing device of claim 8 , wherein each of the plurality of optical channels is configured to guide the light from a corresponding input opening through a corresponding optical channel.

10. The sample sensing device of claim 6 , wherein each of the plurality of optical channels comprises a curved portion and a straight portion.

11. The sample sensing device of claim 1 , wherein the waveguide component comprises:

a substrate layer;

an intermediate layer attached on the substrate layer; and

a waveguide layer attached on the intermediate layer.

12. The sample sensing device of claim 11 , wherein a first edge of the waveguide layer comprises an input opening, wherein a second edge of the waveguide layer comprises an output opening.

13. The sample sensing device of claim 12 , wherein the first edge of the waveguide layer comprises a recessed optical edge.

14. The sample sensing device of claim 12 , wherein the second edge of the waveguide layer comprises a recessed optical edge.

15. The sample sensing device of claim 12 , further comprising:

a light source component coupled to the first edge of the waveguide layer.

16. The sample sensing device of claim 11 , further comprising:

a cover glass component attached to the waveguide component with on-chip fluidics.

17. The sample sensing device of claim 16 , further comprising:

an on-chip fluidics layer attached to a top surface of the waveguide layer.

18. The sample sensing device of claim 16 , further comprising:

an adhesive layer attached on a top surface of the waveguide component with on-chip fluidics.

19. The sample sensing device of claim 18 , further comprising:

a cover glass layer attached on a top surface of the adhesive layer.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 17, 2021
From: VENKATARAYALU, SURESH; FENG, CHEN; SHAFAI, MOIN
To: HAND HELD PRODUCTS, INC.
Reel/Frame 057517/0250 →
Continuity (5)
Continuation 17302536 · May 5, 2021
Provisional Application 63154476 · Feb 26, 2021
Provisional Application 63198609 · Oct 29, 2020
Provisional Application 63021416 · May 7, 2020
Related Publication 20220003667A1 · Jan 6, 2022
References Cited (349)
US 4564021A · Siegmann et al. · 1986 [cited by applicant]
US 5787885A · Lemelson · 1998 [cited by applicant]
US 5961924A · Reichert et al. · 1999 [cited by applicant]
US 6033368A · Gaston et al. · 2000 [cited by applicant]
US 6192168B1 · Feldstein et al. · 2001 [cited by applicant]
US 6618536B1 · Heideman et al. · 2003 [cited by applicant]
US 6624894B2 · Olszak et al. · 2003 [cited by applicant]
US 6846638B2 · Shipwash · 2005 [cited by applicant]
US 6903820B2 · Wang · 2005 [cited by applicant]
US 6955650B2 · Mault et al. · 2005 [cited by applicant]
US 7024066B1 · Malendevich et al. · 2006 [cited by applicant]
US 7048776B2 · Moore et al. · 2006 [cited by applicant]
US 7052854B2 · Melker et al. · 2006 [cited by applicant]
US 7313280B2 · Murai et al. · 2007 [cited by applicant]
US 7347825B2 · Vaughan et al. · 2008 [cited by applicant]
US 8279445B2 · Dominguez Horna et al. · 2012 [cited by applicant]
US 8279448B2 · Kim et al. · 2012 [cited by applicant]
US 8323586B2 · Zhou et al. · 2012 [cited by applicant]
US 8361392B2 · Lee et al. · 2013 [cited by applicant]
US 8403178B2 · May et al. · 2013 [cited by applicant]
US 8654344B2 · Borot et al. · 2014 [cited by applicant]
US 8928875B2 · Braeckmans et al. · 2015 [cited by applicant]
US 9004736B1 · Srinivas et al. · 2015 [cited by applicant]
US 9157804B2 · Messerschmidt · 2015 [cited by applicant]
US 9169521B1 · Rajagopal et al. · 2015 [cited by applicant]
US 9202833B2 · Mackey · 2015 [cited by applicant]
US 9257814B1 · Djordjevic et al. · 2016 [cited by applicant]
US 9273949B2 · Bornhop et al. · 2016 [cited by applicant]
US 9310185B2 · Lloret Soler · 2016 [cited by examiner]
US 9322767B2 · Ehrenkranz · 2016 [cited by applicant]
US 9450381B1 · Cai et al. · 2016 [cited by applicant]
US 9638858B2 · Luo et al. · 2017 [cited by applicant]
US 9690093B2 · Margallo Balbá et al. · 2017 [cited by applicant]
US 9739594B2 · Koerner et al. · 2017 [cited by applicant]
US 9804510B2 · Hamaya et al. · 2017 [cited by applicant]
US 9964703B2 · Parker et al. · 2018 [cited by applicant]
US 9976844B2 · Lloret Soler et al. · 2018 [cited by applicant]
US 9988691B2 · Sislian et al. · 2018 [cited by applicant]
US 10042131B1 · Lesea · 2018 [cited by applicant]
US 10261013B2 · Bornhop et al. · 2019 [cited by applicant]
US 10359417B2 · Hammarlund et al. · 2019 [cited by applicant]
US 10473665B2 · Trowell et al. · 2019 [cited by applicant]
US 10527784B1 · Koste et al. · 2020 [cited by applicant]
US 10591284B2 · Deck et al. · 2020 [cited by applicant]
US 10591460B1 · Ahmad et al. · 2020 [cited by applicant]
US 10627210B2 · Habrich · 2020 [cited by applicant]
US 10670939B2 · Liu et al. · 2020 [cited by applicant]
US 20020034457A1 · Reichert et al. · 2002 [cited by applicant]
US 20020057884A1 · Hirose · 2002 [cited by examiner]
US 20020196450A1 · Olszak et al. · 2002 [cited by applicant]
US 20030152304A1 · Gonthier et al. · 2003 [cited by applicant]
US 20040061864A1 · Snyder et al. · 2004 [cited by applicant]
US 20040081384A1 · Datesman · 2004 [cited by examiner]
US 20040127808A1 · Vaughan et al. · 2004 [cited by applicant]
US 20040149777A1 · Santagiuliana · 2004 [cited by applicant]
US 20040161804A1 · McCash et al. · 2004 [cited by applicant]
US 20040239944A1 · Shirai et al. · 2004 [cited by applicant]
US 20050048599A1 · Goldberg et al. · 2005 [cited by applicant]
US 20050140860A1 · Olczak · 2005 [cited by applicant]
US 20060051010A1 · Chu et al. · 2006 [cited by applicant]
US 20070062255A1 · Talton · 2007 [cited by applicant]
US 20070102362A1 · Iida et al. · 2007 [cited by applicant]
US 20070211254A1 · Matsushita et al. · 2007 [cited by applicant]
US 20070223002A1 · Masri et al. · 2007 [cited by applicant]
US 20080186504A1 · Kiesel et al. · 2008 [cited by applicant]
US 20080204747A1 · Emmerson et al. · 2008 [cited by applicant]
US 20090040524A1 · Joung · 2009 [cited by applicant]
US 20090140048A1 · Yu et al. · 2009 [cited by applicant]
US 20090152267A1 · May et al. · 2009 [cited by applicant]
US 20090255953A1 · May et al. · 2009 [cited by applicant]
US 20100009456A1 · Prins et al. · 2010 [cited by applicant]
US 20100188665A1 · Dotson et al. · 2010 [cited by applicant]
US 20100271634A1 · Dominguez Horna et al. · 2010 [cited by applicant]
US 20110109897A1 · Bataillou et al. · 2011 [cited by applicant]
US 20110236273A1 · Claussen et al. · 2011 [cited by applicant]
US 20110310378A1 · Froggatt et al. · 2011 [cited by applicant]
US 20120085761A1 · Gonzalez · 2012 [cited by applicant]
US 20120147228A1 · Duparré et al. · 2012 [cited by applicant]
US 20120174650A1 · Ariessohn et al. · 2012 [cited by applicant]
US 20120214707A1 · Ymeti et al. · 2012 [cited by applicant]
US 20120231548A1 · Akers, Jr. · 2012 [cited by applicant]
US 20130142477A1 · Diemeer · 2013 [cited by applicant]
US 20130231548A1 · Brown et al. · 2013 [cited by applicant]
US 20130321677A1 · Cote et al. · 2013 [cited by applicant]
US 20140080729A1 · Grego et al. · 2014 [cited by applicant]
US 20140220606A1 · Puntambekar et al. · 2014 [cited by applicant]
US 20140311350A1 · Campbell et al. · 2014 [cited by applicant]
US 20150129768A1 · Koizumi et al. · 2015 [cited by applicant]
US 20150226609A1 · Cho · 2015 [cited by applicant]
US 20150268161A1 · Song et al. · 2015 [cited by applicant]
US 20150276588A1 · Marshall et al. · 2015 [cited by applicant]
US 20160022946A1 · Sislian et al. · 2016 [cited by applicant]
US 20160041138A1 · Pycke et al. · 2016 [cited by applicant]
US 20160187333A1 · Moll et al. · 2016 [cited by applicant]
US 20160327743A1 · Kippenberg et al. · 2016 [cited by applicant]
US 20160349454A1 · Zhang et al. · 2016 [cited by applicant]
US 20170016638A1 · Yun · 2017 [cited by applicant]
US 20170028403A1 · Krause · 2017 [cited by applicant]
US 20170067882A1 · Bornhop et al. · 2017 [cited by applicant]
US 20170097287A1 · Clavaguera et al. · 2017 [cited by applicant]
US 20170303822A1 · Allsworth et al. · 2017 [cited by applicant]
US 20170303823A1 · Allsworth et al. · 2017 [cited by applicant]
US 20170324482A1 · Kato et al. · 2017 [cited by applicant]
US 20170370703A1 · Wang et al. · 2017 [cited by applicant]
US 20180003706A1 · Mavinkurve et al. · 2018 [cited by applicant]
US 20180128600A1 · Wim · 2018 [cited by applicant]
US 20180128680A1 · Kim · 2018 [cited by applicant]
US 20180147573A1 · Hiddessen et al. · 2018 [cited by applicant]
US 20180155782A1 · Zhong · 2018 [cited by applicant]
US 20180250671A1 · De et al. · 2018 [cited by applicant]
US 20180306775A1 · Beck et al. · 2018 [cited by applicant]
US 20190167152A1 · Weda et al. · 2019 [cited by applicant]
US 20190255474A1 · Ryan et al. · 2019 [cited by applicant]
US 20190275357A1 · Palmer, Jr. et al. · 2019 [cited by applicant]
US 20190339466A1 · Heck et al. · 2019 [cited by applicant]
US 20200006088A1 · Yu et al. · 2020 [cited by applicant]
US 20200025611A1 · Mai et al. · 2020 [cited by applicant]
US 20200025631A1 · Howells et al. · 2020 [cited by applicant]
US 20200096450A1 · Zhong et al. · 2020 [cited by applicant]
US 20200132605A1 · Fung et al. · 2020 [cited by applicant]
US 20200220329A1 · Siriani et al. · 2020 [cited by applicant]
US 20210016276A1 · Chiu et al. · 2021 [cited by applicant]
US 20210076979A1 · O'Brien et al. · 2021 [cited by applicant]
US 20210302650A1 · Song et al. · 2021 [cited by applicant]
US 20210349018A1 · Venkatarayalu et al. · 2021 [cited by applicant]
US 20210370289A1 · Klein et al. · 2021 [cited by applicant]
US 20220003670A1 · McBrady et al. · 2022 [cited by applicant]
US 20220003673A1 · Denomme et al. · 2022 [cited by applicant]
AU 2013204332B2 · 2015 [cited by applicant]
CN 102288293A · 2011 [cited by applicant]
CN 102322876A · 2012 [cited by applicant]
CN 103884683B · 2016 [cited by applicant]
CN 106482834A · 2017 [cited by applicant]
CN 106908405A · 2017 [cited by applicant]
CN 107101575A · 2017 [cited by applicant]
CN 207570561U · 2018 [cited by applicant]
CN 108592964A · 2018 [cited by applicant]
CN 208311016U · 2019 [cited by applicant]
CN 109946463A · 2019 [cited by applicant]
CN 110077703A · 2019 [cited by applicant]
CN 110081817A · 2019 [cited by applicant]
CN 110112649A · 2019 [cited by applicant]
CN 209215662U · 2019 [cited by applicant]
CN 110401101A · 2019 [cited by applicant]
CN 209878413U · 2019 [cited by applicant]
CN 110672556A · 2020 [cited by applicant]
CN 110703385A · 2020 [cited by applicant]
CN 210149831U · 2020 [cited by applicant]
CN 210405999U · 2020 [cited by applicant]
CN 210427333U · 2020 [cited by applicant]
EP 2017602A1 · 2009 [cited by applicant]
EP 3907494A1 · 2021 [cited by applicant]
EP 4239318A2 · 2023 [cited by applicant]
GB 2437543A · 2006 [cited by applicant]
JP 07084135A · 1995 [cited by applicant]
JP 11500826A · 1999 [cited by applicant]
JP 2000230890A · 2000 [cited by applicant]
JP 2002507287A · 2002 [cited by applicant]
JP 2002098844A · 2002 [cited by applicant]
JP 2002541492A · 2002 [cited by applicant]
JP 2003004752A · 2003 [cited by applicant]
JP 2004125624A · 2004 [cited by applicant]
JP 2004145246A · 2004 [cited by applicant]
JP 2004537038A · 2004 [cited by applicant]
JP 2005234538A · 2005 [cited by applicant]
JP 2007531863A · 2007 [cited by applicant]
JP 2008506940A · 2008 [cited by applicant]
JP 2011509225A · 2011 [cited by applicant]
JP 2013509581A · 2013 [cited by applicant]
JP 2013238401A · 2013 [cited by applicant]
JP 2014509732A · 2014 [cited by applicant]
JP 2015152491A · 2015 [cited by applicant]
JP 2016512431A · 2016 [cited by applicant]
JP 2016166917A · 2016 [cited by applicant]
JP 2017503162A · 2017 [cited by applicant]
JP 2017161355A · 2017 [cited by applicant]
JP 2020020990 · 2020 [cited by applicant]
JP 2020523551A · 2020 [cited by applicant]
JP 2020153862A · 2020 [cited by applicant]
KR 100839268B1 · 2008 [cited by applicant]
KR 1020150059436A · 2015 [cited by applicant]
RU 2690319C1 · 2019 [cited by applicant]
WO 1998044970A1 · 1998 [cited by applicant]
WO 2004020987A1 · 2004 [cited by applicant]
WO 2005054826A1 · 2005 [cited by applicant]
WO 2009010624A1 · 2009 [cited by applicant]
WO 2009022028A1 · 2009 [cited by applicant]
WO 2010090599A1 · 2010 [cited by applicant]
WO 2017153378A1 · 2017 [cited by applicant]
WO 2018143474A1 · 2018 [cited by applicant]
WO 2018185489A1 · 2018 [cited by applicant]
WO 2019178247A1 · 2019 [cited by applicant]
WO 2020005431A1 · 2020 [cited by applicant]
WO 2020031751A1 · 2020 [cited by applicant]
WO 2020037307A1 · 2020 [cited by applicant]
WO 2020071273A1 · 2020 [cited by applicant]
WO 2020141463A2 · 2020 [cited by applicant]
WO 2021202929A1 · 2021 [cited by applicant]
English Translation of JP Office Action dated Sep. 29, 2023 for JP Application No. 2022152938, 1 page(s). [cited by applicant]
European search report Mailed on Oct. 23, 2023 for EP Application No. 23152603, 11 page(s). [cited by applicant]
JP Office Action Mailed on Sep. 29, 2023 for JP Application No. 2022152938, 2 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Aug. 10, 2023 for U.S. Appl. No. 17/302,535, 8 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Aug. 10, 2023 for U.S. Appl. No. 17/446,686, 3 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Aug. 17, 2023 for U.S. Appl. No. 17/446,688, 3 page(s). [cited by applicant]
Extended European Search Report issued in European Application No. 21172819.1 on Sep. 24, 2021, 12 pages. [cited by applicant]
Requirement for Restriction/Election Mailed on Jan. 11, 2024 for U.S. Appl. No. 17/933,678, 8 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Aug. 7, 2023 for U.S. Appl. No. 17/446,684, 3 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Aug. 7, 2023 for U.S. Appl. No. 17/446,688, 8 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Sep. 13, 2023 for U.S. Appl. No. 17/302,535, 3 page(s). [cited by applicant]
Kratskin, Igor et al., “An Easily Constructed Pipette for Pressure Microinjections Into the Brain,” Brain Research Bulletin, 44(2):199-203, (1997). [cited by applicant]
Non-Final Rejection Mailed on Nov. 18, 2022 for U.S. Appl. No. 17/302,535. [cited by applicant]
EP Office Action Mailed on Sep. 27, 2023 for EP Application No. 21172819, 5 page(s). [cited by applicant]
Final Rejection Mailed on Apr. 11, 2023 for U.S. Appl. No. 17/302,535, 12 page(s). [cited by applicant]
Final Rejection Mailed on Apr. 11, 2023 for U.S. Appl. No. 17/446,684, 17 page(s). [cited by applicant]
Igor L Kratskin, XiaosongYu, Richard L Doty, An Easily Constructed Pipette for Pressure Microinjections Into the Brain, Brain Research Bulletin, vol. 44, Issue 2, 1997, pp. 199-203, ISSN 0361-9230,https://doi.org/10.101… [cited by applicant]
List of references Mailed on Apr. 3, 2023 for U.S. Appl. No. 17/446,686, 1 page(s). [cited by applicant]
List of references Mailed on Apr. 11, 2023 for U.S. Appl. No. 17/302,535, 1 page(s). [cited by applicant]
Non-Final Rejection Mailed on Apr. 3, 2023 for U.S. Appl. No. 17/446,686, 17 page(s). [cited by applicant]
Non-Final Rejection Mailed on Apr. 5, 2023 for U.S. Appl. No. 17/446,688, 19 page(s). [cited by applicant]
Patil, Satyashodhan. “Technical Considerations for Designing Syringes and Other Drug-Delivery Devices.” Mddionline.com, Jul. 23, 2019, https://www.mddionline.com/design-engineering/designing-drug-delivery-device-read-fi… [cited by applicant]
European search report Mailed on Oct. 2, 2023 for EP Application No. 23177883, 7 page(s). [cited by applicant]
English Translation of JP Office Action dated Oct. 10, 2023 for JP Application No. 2022160389, 2 page(s). [cited by applicant]
JP Office Action Mailed on Oct. 10, 2023 for JP Application No. 2022160389, 3 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Aug. 31, 2023 for U.S. Appl. No. 17/446,684, 3 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Aug. 31, 2023 for U.S. Appl. No. 17/446,686, 3 page(s). [cited by applicant]
List of references Mailed on Nov. 25, 2022 for U.S. Appl. No. 17/446,684. [cited by applicant]
Non-Final Rejection Mailed on Nov. 25, 2022 for U.S. Appl. No. 17/446,684. [cited by applicant]
Partial European Search Report for EP No. 22197548.5 received Feb. 16, 2023. [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jul. 26, 2023 for U.S. Appl. No. 17/446,684, 3 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jul. 27, 2023 for U.S. Appl. No. 17/446,686, 9 page(s). [cited by applicant]
Advisory Action (PTOL-303) Mailed on Jul. 10, 2023 for U.S. Appl. No. 17/302,535, 3 page(s). [cited by applicant]
European search report Mailed on Jul. 17, 2023 for EP Application No. 23152603, 14 page(s). [cited by applicant]
European search report Mailed on Nov. 9, 2021 for EP Application No. 21172819, 8 page(s). [cited by applicant]
European search report Mailed on Sep. 24, 2021 for EP Application No. 21172749, 12 page(s). [cited by applicant]
Examiner Interview Summary Record (PTOL-413) Mailed on Jul. 10, 2023 for U.S. Appl. No. 17/302,535, 1 page(s). [cited by applicant]
Non-Final Rejection Mailed on Nov. 18, 2022 for U.S. Appl. No. 17/302,535, 16 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jul. 12, 2023 for U.S. Appl. No. 17/446,684, 8 page(s). [cited by applicant]
Sevin-Landais et al., “Functional immobilisation of the nicotinic acetylcholine receptor in tethered lipid membranes,” Biophysical Chemistry, 85:141-152, (2000). [cited by applicant]
“Industry News: New ‘saliva test’ to instantly detect coronavirus with lasers,” Select Science Apr. 7, 2020, (5 pages), https://www.selectscience.net/industry-news/new-saliva-test-to-instantly-detect-coronavirus-with-la… [cited by applicant]
“Integrate Breath Biopsy.” Owlstone Medical, https://www.owlstonemedical.com/breath-biopsy-covid-19-research/. [cited by applicant]
“Interferometry explained,” Renishaw, https://www.renishaw.com/en/interferometry-explained--7854. [cited by applicant]
Agranovski, et al. “Comparative Study of the Performance of Nine Filters Utilized in Filtration of Aerosols by Bubbling,” Aerosol Science and Technology, 2001, 35:4, 852-859, DOI: 10.1080/027868201753227415. [cited by applicant]
Agranovski, et al. “New personal sampler for viable airborne viruses: feasibility study,” Journal of Aerosol Science, vol. 36, Issues 5-6, 2005, pp. 609-617. https://doi.org/10.1016/j.jaerosci.2004.11.014. [cited by applicant]
Azevedo, M. “E25Bio Raises $2M From Khosla Ventures to Create Rapid COVID-19 Diagnostic Test,” Crunchbase News, Mar. 18, 2020. https://news.crunchbase.com/news/e25bio-raises-2m-from-khosla-ventures-to-create-rapid-covid… [cited by applicant]
Bellamy III, W. “Halo Sensor Advances IoT Concept of Wireless Cabin Air Quality Monitoring,” Aviation Today, Jun. 12, 2020 (7 pages). https://www.aviationtoday.com/2020/06/12/halo-sensor-advances-iot-concept-wireless-ca… [cited by applicant]
BioOptics World Editors. “Optical method could cut Coronavirus diagnosis time to 15 minutes,” Laser Focus World, Mar. 10, 2020 (5 pages). https://www.laserfocusworld.com/biooptics/biomedicine/article/14195374/optical-me… [cited by applicant]
BioPhotonics, “Plasmonic Biosensor Uses Thermal and Optical Methods to Detect Coronavirus,” Photonics Media, Jul./Aug. 2020, https://www.photonics.com/Articles/Plasmonic_Biosensor_Uses_Thermal_and_Optical/a65734. [cited by applicant]
Campbell D.P. (2008) Interferometric Biosensors. In: Zourob M., Elwary S., Turner A. (eds) Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems. Springer, New York, NY. https://doi.org/1… [cited by applicant]
Chaghajerdi, A. “Sensing and Control in Optical Drives: How to Read Data from a Clear Disc,” in IEEE Control Systems Magazine, vol. 28, No. 3, pp. 23-29, Jun. 2008, doi: 10.1109/MCS.2008.920436. [cited by applicant]
Collimation of Astigmatic Diode Laser Beam by Objective Lens, LightTrans International GmbH. Retrieved from https://www.lighttrans.com/fileadmin/shared/UseCases/Application_UC_Collimation%20of%20Astigmatic%20Diode%20Las… [cited by applicant]
Communication from Photonics 21. “Photonics21 to develop saliva test to detect Covid-19 with lasers,” Science Business, Apr. 7, 2020 (6 pages). https://sciencebusiness.net/network-updates/photonics21-develop-saliva-test… [cited by applicant]
Covid-19 diagnose, faster and cheaper, nanbiosis (2 pages). https://www.nanbiosis.es/covid-19-diagnose-faster-and-cheaper/. [cited by applicant]
Deck, L. “High-performance multi-channel fiber-based absolute distance measuring interferometer system,” Proceedings vol. 7405, Instrumentation, Metrology, and Standards for Nanomanufacturing III; 74050E (2009), 9 pages… [cited by applicant]
Duval, et al. “Nanophotonic lab-on-a-chip platforms including novel bimodal interferometers, microfluidics and grating couplers,” Lab on a chip, 2012, 12(11): 1987-1994. 10.1039/c2lc40054e. [cited by applicant]
Extended European Search Report issued in European Application No. 21172819.1 on Nov. 9, 2021, 9 pages. [cited by applicant]
Gao, et al. “Airborne Wireless Sensor Networks for Airplane Monitoring System,” Hindawi Wireless Communications and Mobile Computing, vol. 2018, Article ID 6025825, 18 pages. DOI: https://doi.org/10.1155/2018/6025825. [cited by applicant]
Garcia, D. Lab-on-A-Chip Integration of the Bimodal Waveguide Nanointerferometric Biosensor. 2018. Autonomous University of Barcelona. PhD Dissertation. [cited by applicant]
Gonzélez, Ana Belen. A Bimodal Waveguide Interferometer Device Based on Silicon Photonics Technology for Label-free and High Sensitive Biosensing. 2012. The Autonomous University of Barcelona. PhD Thesis. [cited by applicant]
González-Guerrero, et al. “Advanced photonic biosensors for point-of-care diagnostics,” Procedia Engineering, vol. 25, 2011, pp. 71-75, ISSN 1877-7058. DOI:https://doi.org/10.1016/j.proeng.2011.12.018. [cited by applicant]
Halo IOT Smart Sensor [retrieved on Dec. 15, 2021] retrieved on the internet from <URL:https://ipvideocorp.com/halo/> (15 pages). [cited by applicant]
Halo IOT Smart Sensor Mechanical Specifications. IPVideoCorp. https://ipvideocorp.com/halo-tech-specs/. [cited by applicant]
Halo Smart Sensor. IP Video Corp. https://ipvideocorp.com/wp-content/uploads/2020/02/HALO_General_2.10.20.pdf. [cited by applicant]
Hamed, A. “Image Processing of Corona Virus Using Interferometry,” Optics and Photonics Journal, 2016, 6, 75-86. [cited by applicant]
Hong, et al. “Gentle Sampling of Submicrometer Airborne Virus Particles using a Personal Electrostatic Particle Concentrator” Environ. Sci. Technol. 2016, 50, 22, 12365-12372. [cited by applicant]
Liang, et al. “Bimodal Waveguide Interferometer RI Sensor Fabricated on Low-Cost Polymer Platform,” IEEE Photonics Journal, vol. 11, No. 2, pp. 1-8, Apr. 2019, Art No. 6801108, doi: 10.1109/JPHOT.2019.2900741. [cited by applicant]
Martino, et al. “Reference interferometer using a semiconductor laser/LED reference source in a cryogenic Fourier-transform spectrometer,” Proceedings, Cryogenic Optical Systems and Instruments VIII, 1998, vol. 3435, 19… [cited by applicant]
McDevitt, et al. “Development and Performance Evaluation of an Exhaled-Breath Bioaerosol Collector,” Aerosol Sci Technology, 2013, 47(4):444-451. doi: 10.1080/02786826.2012.762973. [cited by applicant]
Miller, et al. “A Handheld Electrostatic Precipitator for Sampling Airborne Particles and Nanoparticles,” Aerosol Science and Technology, 2010, 44:6, 417-427, DOI: 10.1080/02786821003692063. [cited by applicant]
National Research Council. 2002. The Airliner Cabin Environment and the Health of Passengers and Crew. Washington, DC: The National Academies Press.https://doi.org/10.17226/10238. [cited by applicant]
New research projects on Coronavirus, Oct. 22, 2020, European Commission (4 pages). https://ec.europa.eu/info/sites/default/files/research_and_innovation/research_by_area/documents/ec_rtd_cv-projects.pdf. [cited by applicant]
Ruiz-Vega, et al. “Nanophotonic biosensors for point-of-care COVID-19 diagnostics and coronavirus surveillance,” J. Phys. Photonics 3 (2021) 011002, pp. 1-8. [cited by applicant]
SARS-COV-2 Airborne Detection. Smiths Detection. https://www.smithsdetection.com/. [cited by applicant]
Schmit, Joanna. An Introduction to non-contact surface metrology. 2007, https://cupdf.com/document/an-introduction-to-non-contact-surface-metrology-dr-an-introduction-to-non-contact.html. [cited by applicant]
Trafton, et al. “Covid-19 diagnostic based on MIT technology might be tested on patient samples soon,” MIT News on Campus and Around the World, Massachusetts Institute of Technology, Mar. 12, 2020, https://news.mit.edu/… [cited by applicant]
Usachev, et al. “Multiplexed Surface Plasmon Resonance based real time viral aerosol detection,” Journal of Aerosol Science, 90 (2015): 136-143. https://doi.org/10.1016/j.jaerosci.2015.08.009. [cited by applicant]
Wallace, J. “New saliva test to instantly detect coronavirus via interferometric laser technology,” Laser Focus World, Apr. 7, 2020 (7 pages). https://www.laserfocusworld.com/test-measurement/article/14173589/new-saliva… [cited by applicant]
Waltz, E. “Can Sensors that Detect Coronavirus in the Air Help Economies Reopen Safely?” IEEE Spectrum, Jun. 18, 2020, https://spectrum.ieee.org/devices-monitor-coronavirus-in-the-air. [cited by applicant]
Wragg, et al. “An automated online instrument to quantify aerosol-bound reactive oxygen species (ROS) for ambient measurement and health-relevant aerosol studies,” in Atmos. Meas. Tech., 9, 4891-4900, 2016. doi:10.5194/… [cited by applicant]
Ymeti, A. Development of a multichannel integrated young interferometer immunosensor. 2004. PhD Thesis. University of Twente. [cited by applicant]
Zinoviev, et al. “Integrated Bimodal Waveguide Interferometric Biosensor for Label-Free Analysis,” in Journal of Lightwave Technology, 2011, vol. 29, No. 13, pp. 1926-1930, doi: 10.1109/JLT.2011.2150734. [cited by applicant]
Non-Final Rejection Mailed on Mar. 29, 2024 for U.S. Appl. No. 17/302,536, 16 page(s). [cited by applicant]
Final Rejection Mailed on Sep. 6, 2024 for U.S. Appl. No. 17/933,678, 22 page(s). [cited by applicant]
Non-Final Rejection Mailed on Sep. 11, 2024 for U.S. Appl. No. 17/447,996, 15 page(s). [cited by applicant]
Non-Final Rejection Mailed on Sep. 11, 2024 for U.S. Appl. No. 17/447,998, 8 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Sep. 5, 2024 for U.S. Appl. No. 17/302,536, 10 page(s). [cited by applicant]
Stamm, Ch., and W. Lukosz. “Integrated Optical Difference Interferometer as immunosensor.” Sensors and Actuators B: Chemical, vol. 31, No. 3, Mar. 1996, pp. 203-207, https://doi.org/10.1016/0925-4005(96)80067-0 (Year: 1… [cited by applicant]
Non-Final Rejection Mailed on Apr. 11, 2024 for U.S. Appl. No. 17/933,678, 20 page(s). [cited by applicant]
English Translation of JP Notice of Allowance, including Search Report dated Oct. 11, 2024 for JP Application No. 2021079086, 2 page(s). [cited by applicant]
JP Notice of Allowance, including Search Report Mailed on Oct. 11, 2024 for JP Application No. 2021079086, 4 page(s). [cited by applicant]
European search report Mailed on Apr. 4, 2024 for EP Application No. 22199404, 12 page(s). [cited by applicant]
European partial search report Mailed on May 3, 2024 for EP Application No. 23213622, 11 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Sep. 20, 2024 for U.S. Appl. No. 17/302,536, 2 page(s). [cited by applicant]
English translation of JP Decision to Grant dated Feb. 2, 2024 for JP Application No. 2022152938, 2 page(s). [cited by applicant]
JP Decision to Grant Mailed on Feb. 2, 2024 for JP Application No. 2022152938, 3 page(s). [cited by applicant]
EP Office Action Mailed on May 28, 2024 for EP Application No. 22197548, 9 page(s). [cited by applicant]
Final Rejection Mailed on Sep. 23, 2024 for U.S. Appl. No. 18/503,902, 16 page(s). [cited by applicant]
English Translation of JP Office Action dated Feb. 9, 2024 for JP Application No. 2021079086, 5 page(s). [cited by applicant]
JP Office Action Mailed on Feb. 9, 2024 for JP Application No. 2021079086, 6 page(s). [cited by applicant]
EP Office Action Mailed on Mar. 13, 2024 for EP Application No. 21172749, 7 page(s). [cited by applicant]
Requirement for Restriction/Election Mailed on Oct. 4, 2024 for U.S. Appl. No. 17/447,995, 7 page(s). [cited by applicant]
Communication about intention to grant a European patent Mailed on Sep. 18, 2024 for EP Application No. 21172819, 6 page(s). [cited by applicant]
Requirement for Restriction/Election Mailed on Dec. 5, 2024 for U.S. Appl. No. 17/936,764, 7 page(s). [cited by applicant]
European search report Mailed on Jul. 29, 2024 for EP Application No. 22199404, 14 page(s). [cited by applicant]
Karsunke et al., “Development of a multichannel flow-through chemiluminescence microarray chip for parallel calibration and detection of pathogenic bacteria,” Anal Bioannal Chem, 395:1623-1630, (2009). [cited by applicant]
English Translation of JP Notice of Allowance, including Search Report dated Oct. 1, 2024 for JP Application No. 2022160389, 2 page(s). [cited by applicant]
JP Notice of Allowance, including Search Report Mailed on Oct. 1, 2024 for JP Application No. 2022160389, 3 page(s). [cited by applicant]
European search report Mailed on Sep. 3, 2024 for EP Application No. 23213622, 13 page(s). [cited by applicant]
Non-Final Rejection Mailed on Jun. 14, 2024 for U.S. Appl. No. 18/503,902, 16 page(s). [cited by applicant]
Non-Final Rejection Mailed on Dec. 23, 2024 for U.S. Appl. No. 17/447,995, 21 page(s). [cited by applicant]
Advisory Action (PTOL-303) Mailed on Jan. 13, 2025 for U.S. Appl. No. 18/503,902, 3 page(s). [cited by applicant]
Final Rejection Mailed on Feb. 7, 2025 for U.S. Appl. No. 17/447,998, 10 page(s). [cited by applicant]
Non-Final Rejection Mailed on Feb. 13, 2025 for U.S. Appl. No. 17/936,764, 10 page(s). [cited by applicant]
English Translation of JP Office Action dated Feb. 4, 2025 for JP Application No. 2021079150, 4 page(s). [cited by applicant]
JP Office Action Mailed on Feb. 4, 2025 for JP Application No. 2021079150, 5 page(s). [cited by applicant]
Decision to grant a European patent Mailed on Jan. 23, 2025 for EP Application No. 21172819, 3 page(s). [cited by applicant]
Advisory Action (PTOL-303) Mailed on Feb. 19, 2025 for U.S. Appl. No. 17/933,678, 2 page(s). [cited by applicant]
Examiner Interview Summary Record (PTOL-413) Mailed on Mar. 6, 2025 for U.S. Appl. No. 18/503,902, 1 page(s). [cited by applicant]
Final Rejection Mailed on Feb. 20, 2025 for U.S. Appl. No. 17/447,996, 13 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Mar. 6, 2025 for U.S. Appl. No. 18/503,902, 10 page(s). [cited by applicant]
Requirement for Restriction/Election Mailed on Feb. 27, 2025 for U.S. Appl. No. 18/156,221, 7 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Mar. 25, 2025 for U.S. Appl. No. 18/503,902, 7 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Mar. 28, 2025 for U.S. Appl. No. 18/503,902, 7 page(s). [cited by applicant]
Advisory Action (PTOL-303) Mailed on May 5, 2025 for U.S. Appl. No. 17/447,996, 3 page(s). [cited by applicant]
Non-Final Rejection Mailed on May 8, 2025 for U.S. Appl. No. 18/156,221, 13 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on May 8, 2025 for U.S. Appl. No. 18/503,902, 7 page(s). [cited by applicant]
Advisory Action (PTOL-303) Mailed on Apr. 17, 2025 for U.S. Appl. No. 17/447,998, 3 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Apr. 21, 2025 for U.S. Appl. No. 17/447,995, 12 page(s). [cited by applicant]
Non-Final Rejection Mailed on May 13, 2025 for U.S Appl. No. 17/933,678, 17 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jun. 10, 2025 for U.S. Appl. No. 17/447,995, 10 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jun. 10, 2025 for U.S. Appl. No. 17/447,998, 6 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jun. 11, 2025 for U.S. Appl. No. 18/503,902, 7 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on May 27, 2025 for U.S. Appl. No. 18/503,902, 7 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on May 28, 2025 for U.S. Appl. No. 17/447,998, 9 page(s). [cited by applicant]
Examiner Interview Summary Record (PTOL-413) Mailed on Jun. 24, 2025 for U.S. Appl. No. 17/447,996, 1 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jun. 24, 2025 for U.S. Appl. No. 17/447,996, 11 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jun. 24, 2025 for U.S. Appl. No. 17/447,998, 6 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jul. 1, 2025 for U.S. Appl. No. 17/447,995, 10 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jul. 1, 2025 for U.S. Appl. No. 17/447,996, 8 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jul. 15, 2025 for U.S. Appl. No. 17/447,995, 10 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jul. 15, 2025 for U.S. Appl. No. 17/447,998, 6 page(s). [cited by applicant]
EP Office Action Mailed on Jun. 12, 2025 for EP Application No. 23152603, 6 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jul. 24, 2025 for U.S. Appl. No. 17/447,996, 8 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jul. 25, 2025 for U.S. Appl. No. 17/447,995, 10 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Jul. 25, 2025 for U.S. Appl. No. 17/447,998, 6 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Aug. 1, 2025 for U.S. Appl. No. 17/936,764, 11 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Aug. 6, 2025 for U.S. Appl. No. 17/447,996, 9 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Aug. 6, 2025 for U.S. Appl. No. 17/447,998, 7 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Aug. 11, 2025 for U.S. Appl. No. 17/936,764, 8 page(s). [cited by applicant]
Notice of Allowance and Fees Due (PTOL-85) Mailed on Aug. 15, 2025 for U.S. Appl. No. 17/447,996, 9 page(s). [cited by applicant]