Skin solution with solubilized bakuchiol
A composition for the treatment of acne includes hydrolyzed Psoralea corylifolia , containing a component bakuchiol, is solubilized in a water-based solution. The composition is for topical application to the skin. In various implementations, the composition is a water-based acne gel or a water-based cleanser. In a specific implementation, a composition includes Bakutrol™, which includes bakuchiol, and bisabolol. The composition can include a polysorbate surfactant. In implementations, these ingredients are combined with other active ingredients, including for example, salicylic acid, benzoyl peroxide, tretinoin, retinol, tazarotene, or an antibiotic, or a combination of these. A process of preparation of the composition allows for the stabilization of Bakutrol in solution.
1. A topical composition comprising:
(i) about 0.05 wt % to about 2.00 wt % of bakuchiol;
(ii) about 0.05 wt % to about 2.00 wt % of bisabolol;
(iii) about 0.5 wt % to about 2.00 wt % of salicylic acid;
(iv) about 4.8 wt % to about 22 wt % of decyl glucoside;
(v) one or more skin conditioners;
(vi) Perilla ocymoides leaf extract;
(vii) Olea europaea extract; and
(viii) about 70 wt % to about 99 wt % water.
2. The topical composition of claim 1 further comprising one or more surfactants selected from the group consisting of polysorbate, cocamidopropyl betaine, caprylyl glycol, PPG-2 isoceteth-20-acetate and combinations thereof.
3. The topical composition of claim 1 wherein the one or more skin conditioners are selected from the group consisting of aloe, Sapindus mukurossi extract, dipotassium glycyrrhizate and combinations thereof.
4. The topical composition of claim 1 further comprising a viscosity controlling agent.
5. A method of treating acne comprising applying the composition defined in claim 1 to an area of a subject's skin in need of such treatment.
6. The topical composition of claim 1 wherein the one or more skin conditioners comprises about 0.01 wt % to about 5.0 wt % of Sapindus mukurossi extract.
7. The topical composition of claim 1 wherein the one or more skin conditioners comprises about 0.01 wt % to about 5.0 wt % of dipotassium glycyrrhizate.
8. A topical composition comprising:
(i) about 0.05 wt % to about 2.00 wt % of bakuchiol;
(ii) about 0.05 wt % to about 2.00 wt % of bisabolol;
(iii) about 0.5 wt % to about 2.00 wt % of salicylic acid;
(iv) about 4.8 wt % to about 22 wt % of decyl glucoside;
(v) about 0.01 wt % to about 5.0 wt % of Sapindus mukurossi extract;
(vi) about 0.01 wt % to about 5.0 wt % of dipotassium glycyrrhizate;
(vii) Perilla ocymoides leaf extract;
(viii) Olea europaea extract;
(ix) a viscosity controlling agent; and
(x) about 70 wt % to about 99 wt % water.
9. A method of treating acne comprising applying the composition defined in claim 8 to an area of a subject's skin in need of such treatment.