IP Library Granted Patent US 12,521,321
Granted Patent B2
US 12,521,321 · App. 18/130,092 · Granted Jan 13, 2026

Oral care compositions comprising fluoride

Inventors: Arif Ali Baig (Mason, OH); Min Mao (Deerfield Township, OH); Gregory Charles Gordon (Loveland, OH); Melissa Cherie Payne (West Chester, OH); Holly Balasubramanian Rauckhorst (Ft. Thomas, KY); Paul Albert Sagel (Maineville, OH); Jeanette Marie Swartz (Loveland, OH); Paul Dennis Trokhan (Hamilton, OH); Brian Patrick Croll (Hamilton, OH); Dinah Achola Nyangiro (Mason, OH); Samuel James St. John (Cincinnati, OH); Malgorzata Klukowska (Mason, OH); Michael Anthony Kaminski (Cincinnati, OH); Nataliya Gurich (Cincinnati, OH); Jeremy Clay Christman (Liberty Township, OH)
Assignee: The Procter & Gamble Company
A61K8/0204A61K8/046A61K8/19A61K8/20A61K8/21A61K8/25A61K8/27A61K8/345A61K8/416A61K8/442A61K8/463A61K8/60A61K8/8129A61Q11/00A46B2200/1066A61K8/24A61K8/347A61K8/36A61K2800/28A61K2800/882A61K2800/92A61K2800/95
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Quick Facts
Patent No.
US 12,521,321
App. No.
18/130,092
Granted
Jan 13, 2026
Kind
B2
Abstract

Oral care compositions and/or unit-dose oral care compositions with a fluoride ion source. Oral care compositions and/or unit-dose oral care compositions with a high average fluoride ion uptake. Oral care compositions with one or more web forming materials, a calcium ion source, and a fluoride ion source with a high average fluoride uptake.

Claims (20)

1 . A unit-dose oral care composition comprising:

(a) a fibrous composition comprising web forming material; and

(b) a non-fibrous composition comprising a fluoride ion source,

wherein the unit-dose oral care composition is a solid unit-dose oral care composition.

2 . The unit-dose oral care composition of claim 1 , wherein the fibrous composition comprises a first web and a second web, and the non-fibrous composition is between the first web and the second web.

3 . The unit-dose oral care composition of claim 1 , wherein the fibrous composition is folded on top of the non-fibrous composition.

4 . The unit-dose oral care composition of claim 1 , wherein the fluoride ion source comprises sodium fluoride, sodium monofluorophosphate, stannous fluoride, amine fluoride, or combinations thereof.

5 . The unit-dose oral care composition of claim 1 , wherein the composition comprises from about 0.01% to about 10%, by weight of the unit-dose oral care composition, of a metal ion source, wherein the metal ion source comprises stannous ion source, zinc ion source, or combinations thereof.

6 . The unit-dose oral care composition of claim 1 , wherein the unit-dose oral care composition comprises from about 1% to about 50%, by weight of the unit-dose oral care composition, of the web forming material.

7 . The unit-dose oral care composition of claim 6 , wherein the web forming material comprises starch, polyvinyl alcohol, polyvinyl pyrrolidone, polyethylene oxide, carboxymethylcellulose, polyacrylic acid, polyvinyl ether maleic acid copolymer, or combinations thereof.

8 . The unit-dose oral care composition of claim 1 , wherein the unit-dose oral care composition has from about 0.01% to about 10%, by weight of the unit-dose oral care composition, of the fluoride ion source.

9 . The unit-dose oral care composition of claim 1 , wherein the unit-dose oral care composition has at least about a 1500 ppm fluoride uptake.

10 . The unit-dose oral care composition of claim 1 , wherein the unit-dose oral care composition comprises from about 0.01% to about 40%, by weight of the unit-dose oral care composition, of a calcium ion source.

11 . The unit-dose oral care composition of claim 10 , wherein the calcium ion source comprises calcium abrasive, calcium salt, or combinations thereof.

12 . The unit-dose oral care composition of claim 10 , wherein the unit-dose oral care composition has at least about a 1000 ppm average fluoride uptake.

13 . The unit-dose oral care composition of claim 10 , wherein the fibrous composition comprises the calcium ion source.

14 . The unit-dose oral care composition of claim 10 , wherein the calcium ion source comprises a calcium salt, and the unit-dose oral care composition further comprises an abrasive.

15 . The unit-dose oral care composition of claim 1 , further comprising an abrasive.

16 . The unit-dose oral care composition of claim 1 , wherein the unit-dose oral care composition comprises a salivary fluoride pK AUC that is at least 60% of a reference salivary fluoride pK AUC of a reference standard toothpaste having a reference treatment mass in a range of about 1 g to about 1.25 g when the unit-dose oral care composition is dosed according to manufacturer instructions.

17 . The unit-dose oral care composition of claim 16 , wherein the unit-dose oral care composition comprises a salivary fluoride pK AUC that is at least 80% of the reference salivary fluoride pK AUC.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 10, 2023
From: BAIG, ARIF ALI; GORDON, GREGORY CHARLES; MAO, MIN; PAYNE, MELISSA CHERIE; RAUCKHORST, HOLLY BALASUBRAMANIAN; SAGEL, PAUL ALBERT; SWARTZ, JEANETTE MARIE; TROKHAN, PAUL DENNIS; CROLL, BRIAN PATRICK; NYANGIRO, DINAH ACHOLA; ST.JOHN, SAMUEL JAMES; KLUKOWSKA, MALGORZATA; KAMINSKI, MICHAEL ANTHONY; GURICH, NATALIYA; CHRISTMAN, JEREMY CLAY
To: THE PROCTER & GAMBLE COMPANY
Reel/Frame 064547/0800 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 11, 2023
From: BAIG, ARIF ALI; GORDON, GREGORY CHARLES; MAO, MIN; PAYNE, MELISSA CHERIE; RAUCKHORST, HOLLY BALASUBRAMANIAN; SAGEL, PAUL ALBERT; SWARTZ, JEANETTE MARIE; TROKHAN, PAUL DENNIS; CROLL, BRIAN PATRICK; NYANGIRO, DINAH ACHOLA; ST.JOHN, SAMUEL JAMES
To: THE PROCTER & GAMBLE COMPANY
Reel/Frame 064207/0158 →
Continuity (10)
Continuation 17201023 · Mar 15, 2021
Continuation 17151897 · Jan 19, 2021
Continuation 16411181 · May 14, 2019
Provisional Application 63343569 · May 19, 2022
Provisional Application 63327097 · Apr 4, 2022
Provisional Application 62671072 · May 14, 2018
Provisional Application 62671078 · May 14, 2018
Provisional Application 62671083 · May 14, 2018
Provisional Application 62671066 · May 14, 2018
Related Publication 20230248620A1 · Aug 10, 2023
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