Granted Patent B2

US 12,728,288 · App. 18/974,757 · Granted Sep 8, 2026

Inventors: Binghuan Li (Shanghai, CN); Jingjie Zhou (Shanghai, CN); Jonathan Maltz (Houston, TX)

Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

A61N5/1064A61N5/1031A61N5/1038A61N5/1039A61N5/1049A61N5/1081G16H20/40A61N2005/1052A61N2005/1055A61N2005/1061A61N5/1071

Abstract

Claims (74)

1 . A system for radiation therapy, comprising:

at least one storage device including a set of instructions for adaptive treatment planning; and

at least one processor configured to communicate with the at least one storage device, wherein when executing the set of instructions, the system is directed to perform operations including:

obtaining one or more historical images of a region of interest (ROI) relating to one or more historical treatment plans of the ROI;

obtaining a first guiding image of the ROI, the first guiding image being collected by a first scan of the ROI performed before a first treatment fraction;

determining whether replanning is needed for the first treatment fraction based on the one or more historical images and the first guiding image; and

in response to determining that replanning is not needed for the first treatment fraction, determining a target treatment plan with respect to the first treatment fraction based on the one or more historical treatment plans, or

in response to determining that replanning is needed for the first treatment fraction, generating a notification for reminding a user to reconfirm whether replanning is needed for the first treatment fraction.

2 . The system of claim 1 , wherein the one or more historical images include multiple historical images relating to multiple historical treatment plans,

the determining a target treatment plan with respect to the first treatment fraction comprises:

selecting a historical treatment plan from the historical treatment plans; and

determining the target treatment plan based on the selected historical treatment plan.

3 . The system of claim 2 , wherein the selecting a historical treatment plan from the historical treatment plans comprises:

determining a similarity degree between the first guiding image and each of the historical images; and

selecting, from the historical treatment plans, the historical treatment plan that corresponds to a selected historical image having the greatest similarity degree to the first guiding image.

4 . The system of claim 1 , wherein the one or more historical images include multiple historical images relating to multiple historical treatment plans,

the target treatment plan with respect to the first treatment fraction comprises: generating the target treatment plan by synthesizing the historical treatment plans.

5 . The system of claim 1 , wherein the operations further comprise:

causing a terminal device to present the notification, the first guiding image, and at least part of the one or more historical images;

receiving, from the terminal device, an input of the user regarding whether replanning is needed for the first treatment fraction.

6 . The system of claim 1 , wherein the operations further comprise:

determining a predicted dose distribution with respect to the first treatment fraction based on the first guiding image;

causing a terminal device to present the notification, the predicted dose distribution, and at least part of one or more historical dose distributions corresponding to the one or more historical treatment plans;

receiving, from the terminal device, an input of the user regarding whether replanning is needed for the first treatment fraction.

7 . The system of claim 1 , wherein the first scan is performed with a first dose level, and the determining whether replanning is needed for the first treatment fraction comprises:

generating a simulated image corresponding to a second dose level by processing the first guiding image using an image generation model, the second dose level being higher than the first dose level, and the image generation model being a trained machine learning model;

determining whether replanning is needed for the first treatment fraction based on the one or more historical images and the simulated image.

8 . The system of claim 1 , wherein the determining whether replanning is needed for the first treatment fraction comprises:

determining a predicted dose distribution with respect to the first treatment fraction based on the first guiding image, the one or more historical images, and the one or more historical treatment plans;

determining whether replanning is needed for the first treatment fraction based on the predicted dose distribution.

9 . The system of claim 1 , wherein the first scan is performed with a first dose level, and the operations further comprise:

receiving an input of the user indicating that replanning is needed for the first treatment fraction;

obtaining a second guiding image of the ROI, the second guiding image corresponding to a second dose level higher than the first dose level;

generating the target treatment plan with respect to the first treatment fraction based on the second guiding image.

10 . The system of claim 1 , wherein the one or more historical images include a planning image collected before the radiation therapy, the determining whether replanning is needed for the first treatment fraction comprises:

generating a first comparison result by comparing the planning image with the first guiding image;

generating a second comparison result by comparing the planning image with a historical guiding image acquired during a second treatment fraction prior to the first treatment fraction;

determining whether replanning is needed for the first treatment fraction based on the first comparison result and the second comparison result.

11 . A system for radiation therapy, comprising:

at least one storage device including a set of instructions for adaptive treatment planning; and

at least one processor configured to communicate with the at least one storage device, wherein when executing the set of instructions, the system is directed to perform operations including:

detecting that an updated image is obtained, the updated image relating to a region of interest (ROI) that needs to receive a first treatment fraction;

in response to the detection of the updated image,

obtaining one or more historical images of the ROI relating to one or more historical treatment plans; and

determining whether replanning is needed for the first treatment fraction based on the one or more historical images and the updated image.

12 . The system of claim 11 , wherein the determining whether replanning is needed for the first treatment fraction based on the one or more historical images and the updated image comprises:

determining a predicted dose distribution with respect to the first treatment fraction based on the updated image, the one or more historical images, and the one or more historical treatment plans;

determining whether replanning is needed for the first treatment fraction based on the predicted dose distribution.

13 . The system of claim 12 , wherein whether replanning is needed for the first treatment fraction is determined by determining whether the predicted dose distribution satisfies one or more dose constraints.

14 . The system of claim 12 , wherein the determining whether replanning is needed for the first treatment fraction based on the predicted dose distribution comprises:

generating a comparison result by comparing the predicted dose distribution with at least part of one or more historical dose distributions corresponding to the one or more historical treatment plans; and

determining whether replanning is needed for the first treatment fraction based on the comparison result.

15 . The system of claim 12 , wherein the determining a predicted dose distribution with respect to the first treatment fraction comprises:

generating a registration result between the updated image and each of the one or more historical images;

determining the predicted dose distribution based on the registration result and the one or more historical treatment plans.

16 . The system of claim 12 , wherein the one or more historical images include multiple historical images relating to multiple historical treatment plans,

the determining a predicted dose distribution with respect to the first treatment fraction comprises:

determining a similarity degree between the updated image and each of the historical images;

selecting, from the historical treatment plans, the historical treatment plan that corresponds to a selected historical image having the greatest similarity degree to the updated image; and

determining the predicted dose distribution with respect to the first treatment fraction based on the updated image, the selected historical image, and the selected historical treatment plan.

17 . The system of claim 12 , wherein the one or more historical images include multiple historical images relating to multiple historical treatment plans,

the determining a predicted dose distribution with respect to the first treatment fraction comprises:

for each historical image, determining a candidate dose distribution with respect to the first treatment fraction based on the updated image, the historical image, and the corresponding historical treatment plan;

determining the predicted dose distribution by synthesizing the candidate dose distributions of the historical images.

18 . The system of claim 11 , wherein the operations further include:

in response to determining that replanning is not needed for the first treatment fraction, determining a target treatment plan with respect to the first treatment fraction based on the one or more historical treatment plans, or

in response to determining that replanning is needed for the first treatment fraction, generating a notification for reminding a user to reconfirm whether replanning is needed for the first treatment fraction.

19 . The system of claim 18 , wherein the operations further comprise:

causing a terminal device to present the notification, the updated image, and at least part of the one or more historical images;

receiving, from the terminal device, an input of the user regarding whether replanning is needed for the first treatment fraction.

20 . The system of claim 18 , wherein the operations further comprise:

determining a predicted dose distribution with respect to the first treatment fraction based on the updated image;

causing a terminal device to present the notification, the predicted dose distribution, and at least part of one or more historical dose distributions corresponding to the one or more historical treatment plans;

receiving, from the terminal device, an input of the user regarding whether replanning is needed for the first treatment fraction.

Assignments (3)

Continuity (4)

References Cited (38)