IP Library › Granted Patent US 12,748,209
Granted Patent B2
US 12,748,209 · App. 18/461,442 · Granted Sep 29, 2026

Pulsed illumination in a hyperspectral, fluorescence and laser mapping imaging system

Inventors: Joshua D. Talbert (Cottonwood Heights, UT); Donald M. Wichern (Ogden, UT)
Assignee: Cilag GmbH International
G01S17/89A61B1/00006A61B1/000095A61B1/00194A61B1/043A61B1/05A61B1/0655A61B5/0033A61B5/0071G01J3/2823G01J3/4406G01N21/6456G01S7/4804G01S7/483G06T1/0007G06T7/521H04N23/56H04N23/665H04N23/74G01J2003/1213G01J2003/2826G01J2003/423G01N2201/124G06T2207/10064G06T2207/10068G06T2207/30004H04N23/555
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Quick Facts
Patent No.
US 12,748,209
App. No.
18/461,442
Granted
Sep 29, 2026
Kind
B2
Abstract

Pulsed hyperspectral, fluorescence, and laser mapping imaging in a light deficient environment is disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a controller configured to synchronize timing of the emitter and the image sensor. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises one or more of a hyperspectral emission, a fluorescence emission, or a laser mapping pattern.

Claims (65)

1 . An endoscopic system for providing visualization to a light deficient environment comprising:

an emitter for emitting a plurality of emissions of electromagnetic radiation, wherein the plurality of emissions are a plurality of pulses of electromagnetic radiation;

an image sensor comprising a pixel array, wherein data is read out from the pixel array corresponding to the plurality of pulses of electromagnetic radiation; and

a processor for performing image signal processing, wherein the processor receives the data from the image sensor and generates a plurality of data frames;

a controller in electronic communication with the emitter and the image sensor;

wherein the plurality of emissions of electromagnetic radiation comprises a visible emission of electromagnetic radiation and a spectral emission of electromagnetic radiation for eliciting a spectral response from a tissue, and one or more emission sources comprising:

a mapping emission comprising electromagnetic radiation for generating laser mapping data; or

a fluorescence emission comprising a fluorescence excitation wavelength of electromagnetic radiation;

wherein the controller instructs the emitter to adjust a magnitude, a duration, or a magnitude and a duration of the plurality of emissions of electromagnetic radiation emitted by the emitter;

wherein the plurality of pulses of electromagnetic radiation switch between the visible emission of electromagnetic radiation, the spectral emission, and the one or more emission sources in a pulse cycle pattern; and

wherein the plurality of data frames comprises one or more visible image frames generated from the visible emission of electromagnetic radiation, and one or more exposure frames corresponding to and generated from the spectral emission of electromagnetic radiation and the one or more emission sources.

2 . The system of claim 1 , wherein the emitter pulses the plurality of pulses of electromagnetic radiation for a duration that is during portions of two or more operational cycles of the image sensor.

3 . The system of claim 1 , wherein the magnitude, the duration, or the magnitude and the duration of the plurality of emissions of electromagnetic radiation is adjusted concurrently.

4 . The system of claim 1 , wherein the emitter pulses the mapping emission and the image sensor senses a laser mapping frame comprising the laser mapping data in response to the pulse of the mapping emission, and wherein the laser mapping data comprises data for calculating one or more of a three-dimensional topography of a scene, a dimension of one or more objects within a scene, or a distance.

5 . The system of claim 1 , wherein the spectral emission of electromagnetic radiation comprises one or more of:

electromagnetic radiation comprising a wavelength within a range from about 513 nm to about 545 nm;

electromagnetic radiation comprising a wavelength within a range from about 565 nm to about 585 nm; or

electromagnetic radiation comprising a wavelength within a range from about 900 nm to about 1000 nm.

6 . The system of claim 1 , wherein the fluorescence excitation wavelength of electromagnetic radiation comprises one or more of:

electromagnetic radiation comprising a wavelength within a range from about 770 nm to about 795 nm; or

electromagnetic radiation comprising a wavelength within a range from about 790 nm to about 815 nm.

7 . The system of claim 1 , wherein the controller is configured to synchronize timing of the plurality of emissions of electromagnetic radiation during a blanking period of the image sensor, wherein the blanking period corresponds to a time between a readout of a last row of active pixels in the pixel array and a beginning of a next subsequent readout of active pixels in the pixel array.

8 . The system of claim 7 , wherein the controller is configured to adjust a length of the blanking period to facilitate different blanking periods.

9 . The system of claim 7 , wherein controller is configured to adjust a length of a readout period to facilitate different readout periods.

10 . The system of claim 7 , wherein the emitter begins one or more pulses of the plurality of pulses of electromagnetic radiation during a readout period of the image sensor and ends the one or more pulses of the plurality of pulses of electromagnetic radiation during a readout period of a next succeeding cycle of the image sensor.

11 . The system of claim 8 , wherein the image sensor is configured to facilitate a repeating pattern of different-length blanking periods across operational cycles of the image sensor.

12 . The system of claim 1 , wherein the mapping emission comprises one or more of a raster grid of discrete points, an occupancy grid map, a dot array, vertical hashing, or horizontal hashing.

13 . The system of claim 1 , wherein the image sensor senses a plurality of frame-types in response to the emitter emitting the plurality of emissions of electromagnetic radiation, wherein the plurality of frame-types comprises:

a laser mapping frame sensed in response to the emitter emitting the mapping emission;

a spectral frame sensed in response to the emitter emitting the spectral emission; and

a fluorescence frame sensed in response to the emitter emitting the fluorescence emission.

14 . The system of claim 1 , wherein the processor is configured to execute instructions stored in non-transitory computer readable storage medium, the instructions comprising:

receiving a laser mapping frame sensed by the image sensor, wherein the laser mapping frame is sensed in response to the emitter emitting the mapping emission;

providing the laser mapping frame to a corresponding laser mapping system; and

receiving laser mapping data from the corresponding laser mapping system, wherein the laser mapping data comprises one or more of:

a three-dimensional topographical map of a scene, a dimension of one or more objects within the scene, or a distance.

15 . The system of claim 14 , wherein the instructions further comprise:

receiving a spectral frame sensed by the image sensor, wherein the spectral frame is sensed in response to the emitter emitting the spectral emission;

providing the spectral frame to a corresponding spectral system; and

receiving spectral data from the corresponding spectral system, wherein the spectral data comprises one or more of:

a predicted identity of a tissue structure within the scene; or

a location of the tissue structure within the scene.

16 . The system of claim 14 , wherein the instructions further comprise:

receiving a fluorescence frame sensed by the image sensor, wherein the fluorescence frame is sensed in response to the emitter emitting the fluorescence emission;

providing the fluorescence frame to a corresponding fluorescence system; and

receiving fluorescence data from the corresponding fluorescence system, wherein the fluorescence data comprises one or more of:

a predicted identity of a tissue structure within the scene; or

a location of the tissue structure within the scene.

17 . The system of claim 14 , wherein the instructions further comprise:

receiving the one or more visible image frames of the plurality of visible image frames;

overlaying at least a portion of the laser mapping data, including one of the exposure frames, with at least one of the visible image frames; and

overlaying at least a portion of the fluorescence data, including one of the exposure frames, with the visible image frame.

18 . The system of claim 1 , further comprising:

an endoscope comprising a handpiece and a lumen, wherein the image sensor is disposed substantially near a distal end of the lumen of the endoscope; and

a waveguide for carrying the plurality of emissions of electromagnetic radiation from the emitter to the distal end of the lumen of the endoscope;

wherein the emitter is remote from the endoscope.

19 . The system of claim 1 , wherein the plurality of emissions of electromagnetic radiation further comprises:

a luminance emission comprising a wavelength of electromagnetic radiation that is optimized for sensing luminance data with the image sensor;

a red chrominance emission comprising a wavelength of electromagnetic radiation that is optimized for sensing red-chrominance data with the image sensor; and

a blue chrominance emission comprising a wavelength of electromagnetic radiation that is optimized for sensing blue-chrominance data with the image sensor.

20 . The system of claim 1 , wherein the image signal processing further comprises:

receiving a plurality of independent frames sensed by the image sensor;

performing color correction on the plurality of independent frames;

performing edge enhancement on the plurality of independent frames; and

converting the luminance-chrominance frame to an RGB color image frame.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 5, 2023
From: TALBERT, JOSHUA D; WICHERN, DONALD M
To: DEPUY SYNTHES PRODUCTS, INC.
Reel/Frame 064800/0981 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 5, 2023
From: DEPUY SYNTHES PRODUCTS, INC.
To: ETHICON LLC
Reel/Frame 064800/0996 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 5, 2023
From: ETHICON LLC
To: CILAG GMBH INTERNATIONAL
Reel/Frame 064809/0446 →
Continuity (4)
Continuation 17553573 · Dec 16, 2021
Continuation 16775143 · Jan 28, 2020
Provisional Application 62864231 · Jun 20, 2019
Related Publication 20230417917A1 · Dec 28, 2023
References Cited (316)
US 3844047A · Carson · 1974 [cited by applicant]
US 4556057A · Hiruma et al. · 1985 [cited by applicant]
US 4660982A · Okada · 1987 [cited by applicant]
US 5318024A · Kittrell et al. · 1994 [cited by applicant]
US 5363387A · Sinofky · 1994 [cited by applicant]
US 5515449A · Tsuruoka et al. · 1996 [cited by applicant]
US 5749830A · Kaneko et al. · 1998 [cited by applicant]
US 5784162A · Cabib et al. · 1998 [cited by applicant]
US 6061591A · Freitag et al. · 2000 [cited by applicant]
US 6110106A · MacKinnon et al. · 2000 [cited by applicant]
US 6236879B1 · Konings · 2001 [cited by applicant]
US 6537211B1 · Wang et al. · 2003 [cited by applicant]
US 6937885B1 · Lewis et al. · 2005 [cited by applicant]
US 6975898B2 · Seibel · 2005 [cited by applicant]
US 7826878B2 · Alfano et al. · 2010 [cited by applicant]
US 9509917B2 · Blanquart et al. · 2016 [cited by applicant]
US 9895054B2 · Morimoto et al. · 2018 [cited by applicant]
US 10222474B1 · Raring et al. · 2019 [cited by applicant]
US 10588711B2 · Dicarlo et al. · 2020 [cited by applicant]
US 11006093B1 · Hegyi · 2021 [cited by applicant]
US 11102400B2 · Talbert et al. · 2021 [cited by applicant]
US 11240426B2 · Talbert et al. · 2022 [cited by applicant]
US 11252326B2 · Talbert et al. · 2022 [cited by applicant]
US 11516388B2 · Talbert et al. · 2022 [cited by applicant]
US 11747479B2 · Talbert et al. · 2023 [cited by applicant]
US 11823403B2 · Talbert et al. · 2023 [cited by applicant]
US 20010000317A1 · Yoneya et al. · 2001 [cited by applicant]
US 20020016533A1 · Marchitto et al. · 2002 [cited by applicant]
US 20020026098A1 · Kobayashi · 2002 [cited by applicant]
US 20020065468A1 · Utzinger et al. · 2002 [cited by applicant]
US 20020120182A1 · Muessig et al. · 2002 [cited by applicant]
US 20020123666A1 · Matsumoto · 2002 [cited by applicant]
US 20020138008A1 · Tsujita et al. · 2002 [cited by applicant]
US 20020139920A1 · Seibel et al. · 2002 [cited by applicant]
US 20020161282A1 · Fulghum · 2002 [cited by applicant]
US 20020175993A1 · Ueno et al. · 2002 [cited by applicant]
US 20030058440A1 · Scott et al. · 2003 [cited by applicant]
US 20030059108A1 · Hubel · 2003 [cited by applicant]
US 20030060683A1 · Abe et al. · 2003 [cited by applicant]
US 20030100824A1 · Warren et al. · 2003 [cited by applicant]
US 20030153825A1 · Mooradian et al. · 2003 [cited by applicant]
US 20030157271A1 · Duignan et al. · 2003 [cited by applicant]
US 20030191368A1 · Wang et al. · 2003 [cited by applicant]
US 20030223248A1 · Cronin et al. · 2003 [cited by applicant]
US 20040010192A1 · Benaron et al. · 2004 [cited by applicant]
US 20040092958A1 · Limonadi et al. · 2004 [cited by applicant]
US 20040116800A1 · Helfer et al. · 2004 [cited by applicant]
US 20040119020A1 · Bodkin et al. · 2004 [cited by applicant]
US 20040186351A1 · Imaizumi et al. · 2004 [cited by applicant]
US 20040234152A1 · Liege et al. · 2004 [cited by applicant]
US 20040242961A1 · Bughici · 2004 [cited by applicant]
US 20050020926A1 · Wiklof et al. · 2005 [cited by applicant]
US 20050107808A1 · Evans et al. · 2005 [cited by applicant]
US 20050205758A1 · Almeida · 2005 [cited by applicant]
US 20050240077A1 · Rovegno · 2005 [cited by applicant]
US 20050270528A1 · Geshwind et al. · 2005 [cited by applicant]
US 20060069314A1 · Farr · 2006 [cited by applicant]
US 20060229744A1 · Patzwald et al. · 2006 [cited by applicant]
US 20060239723A1 · Okuda et al. · 2006 [cited by applicant]
US 20060241499A1 · Irion et al. · 2006 [cited by applicant]
US 20060276966A1 · Cotton et al. · 2006 [cited by applicant]
US 20070016077A1 · Nakaoka et al. · 2007 [cited by applicant]
US 20070046778A1 · Ishihara et al. · 2007 [cited by applicant]
US 20070057211A1 · Bahlman et al. · 2007 [cited by applicant]
US 20070086495A1 · Sprague et al. · 2007 [cited by applicant]
US 20070177009A1 · Bayer et al. · 2007 [cited by applicant]
US 20070185384A1 · Bayer et al. · 2007 [cited by applicant]
US 20070242330A1 · Rosman et al. · 2007 [cited by applicant]
US 20070276234A1 · Shahidi · 2007 [cited by applicant]
US 20080058629A1 · Seibel et al. · 2008 [cited by applicant]
US 20080081950A1 · Koenig et al. · 2008 [cited by applicant]
US 20080090220A1 · Freeman et al. · 2008 [cited by applicant]
US 20080174783A1 · Mater · 2008 [cited by applicant]
US 20080177139A1 · Courtney et al. · 2008 [cited by applicant]
US 20080177140A1 · Cline et al. · 2008 [cited by applicant]
US 20080192231A1 · Jureller et al. · 2008 [cited by applicant]
US 20080226029A1 · Weir et al. · 2008 [cited by applicant]
US 20080240502A1 · Freedman et al. · 2008 [cited by applicant]
US 20080249368A1 · Takei · 2008 [cited by applicant]
US 20090051926A1 · Chen · 2009 [cited by applicant]
US 20090289200A1 · Ishii · 2009 [cited by applicant]
US 20090303317A1 · Tesar · 2009 [cited by applicant]
US 20090306478A1 · Mizuyoshi · 2009 [cited by applicant]
US 20100049180A1 · Wells et al. · 2010 [cited by applicant]
US 20100056928A1 · Zuzak et al. · 2010 [cited by applicant]
US 20100128109A1 · Banks · 2010 [cited by applicant]
US 20100157039A1 · Sugai · 2010 [cited by applicant]
US 20100160917A1 · Fitz et al. · 2010 [cited by applicant]
US 20100168585A1 · Fujii · 2010 [cited by applicant]
US 20100261958A1 · Webb et al. · 2010 [cited by applicant]
US 20100277087A1 · Ikeda · 2010 [cited by applicant]
US 20100297659A1 · Yoo · 2010 [cited by applicant]
US 20110069162A1 · Ozawa · 2011 [cited by examiner]
US 20110079714A1 · McEldowney et al. · 2011 [cited by applicant]
US 20110087212A1 · Aldridge et al. · 2011 [cited by applicant]
US 20110196355A1 · Mitchell et al. · 2011 [cited by applicant]
US 20110213252A1 · Fulghum · 2011 [cited by applicant]
US 20110228116A1 · Margalith · 2011 [cited by applicant]
US 20110279679A1 · Samuel et al. · 2011 [cited by applicant]
US 20110280810A1 · Hauger et al. · 2011 [cited by applicant]
US 20110285995A1 · Tkaczyk et al. · 2011 [cited by applicant]
US 20120010465A1 · Erikawa et al. · 2012 [cited by applicant]
US 20120062722A1 · Sase · 2012 [cited by applicant]
US 20120083982A1 · Bonefas et al. · 2012 [cited by applicant]
US 20120105600A1 · Meyer et al. · 2012 [cited by applicant]
US 20120123205A1 · Nie et al. · 2012 [cited by applicant]
US 20120268727A1 · Schrey et al. · 2012 [cited by applicant]
US 20120273470A1 · Zediker et al. · 2012 [cited by applicant]
US 20120294498A1 · Popovic · 2012 [cited by applicant]
US 20130053703A1 · Yamamoto · 2013 [cited by examiner]
US 20130085484A1 · Van Valen et al. · 2013 [cited by applicant]
US 20130176395A1 · Kazakevich · 2013 [cited by applicant]
US 20130211246A1 · Parasher · 2013 [cited by applicant]
US 20130217970A1 · Weisenburgh et al. · 2013 [cited by applicant]
US 20130274596A1 · Azizian et al. · 2013 [cited by applicant]
US 20130324797A1 · Igarashi et al. · 2013 [cited by applicant]
US 20140073885A1 · Frangioni · 2014 [cited by applicant]
US 20140111623A1 · Zhao et al. · 2014 [cited by applicant]
US 20140129037A1 · Peterson · 2014 [cited by applicant]
US 20140160259A1 · Blanquart et al. · 2014 [cited by applicant]
US 20140160260A1 · Blanquart et al. · 2014 [cited by applicant]
US 20140160318A1 · Blanquart · 2014 [cited by examiner]
US 20140163319A1 · Blanquart et al. · 2014 [cited by applicant]
US 20140184089A1 · Porter et al. · 2014 [cited by applicant]
US 20140187879A1 · Wood et al. · 2014 [cited by applicant]
US 20140276093A1 · Zeien · 2014 [cited by applicant]
US 20140300750A1 · Nagamune · 2014 [cited by applicant]
US 20140323878A1 · Toriumi et al. · 2014 [cited by applicant]
US 20140336501A1 · Masumoto · 2014 [cited by applicant]
US 20150044098A1 · Smart et al. · 2015 [cited by applicant]
US 20150073209A1 · Ikeda · 2015 [cited by applicant]
US 20150116539A1 · Nayar et al. · 2015 [cited by applicant]
US 20150132766A1 · Yasuda et al. · 2015 [cited by applicant]
US 20150223733A1 · Al-Alusi · 2015 [cited by applicant]
US 20150305604A1 · Melsky · 2015 [cited by applicant]
US 20150309284A1 · Kagawa et al. · 2015 [cited by applicant]
US 20150338268A1 · Ramer et al. · 2015 [cited by applicant]
US 20150381909A1 · Butte et al. · 2015 [cited by applicant]
US 20160006914A1 · Neumann · 2016 [cited by applicant]
US 20160042513A1 · Yudovsky · 2016 [cited by applicant]
US 20160047750A1 · Berto et al. · 2016 [cited by applicant]
US 20160062103A1 · Yang et al. · 2016 [cited by applicant]
US 20160065938A1 · Kazemzadeh et al. · 2016 [cited by applicant]
US 20160150948A1 · Shimamoto · 2016 [cited by examiner]
US 20160157725A1 · Munoz · 2016 [cited by applicant]
US 20160183775A1 · Blanquart et al. · 2016 [cited by applicant]
US 20160195706A1 · Fujii · 2016 [cited by applicant]
US 20160216288A1 · Hofmeister et al. · 2016 [cited by applicant]
US 20160259058A1 · Verheggen et al. · 2016 [cited by applicant]
US 20160278678A1 · Valdes et al. · 2016 [cited by applicant]
US 20160335778A1 · Smits · 2016 [cited by applicant]
US 20160353039A1 · Rephaeli et al. · 2016 [cited by applicant]
US 20160377722A1 · Lardin et al. · 2016 [cited by applicant]
US 20170003168A1 · Fujii et al. · 2017 [cited by applicant]
US 20170035280A1 · Yang et al. · 2017 [cited by applicant]
US 20170059305A1 · Nonn et al. · 2017 [cited by applicant]
US 20170059408A1 · Körner et al. · 2017 [cited by applicant]
US 20170071472A1 · Zeng et al. · 2017 [cited by applicant]
US 20170086940A1 · Nakamura · 2017 [cited by applicant]
US 20170163971A1 · Wang et al. · 2017 [cited by applicant]
US 20170167980A1 · Dimitriadis et al. · 2017 [cited by applicant]
US 20170185716A1 · Rodriguez et al. · 2017 [cited by applicant]
US 20170205198A1 · Roncone et al. · 2017 [cited by applicant]
US 20170209050A1 · Fengler et al. · 2017 [cited by applicant]
US 20170232269A1 · Luttrull et al. · 2017 [cited by applicant]
US 20170280029A1 · Steiner · 2017 [cited by applicant]
US 20170280970A1 · Sartor et al. · 2017 [cited by applicant]
US 20170293134A1 · Otterstrom et al. · 2017 [cited by applicant]
US 20170360275A1 · Yoshizaki · 2017 [cited by applicant]
US 20180000401A1 · Kang et al. · 2018 [cited by applicant]
US 20180008138A1 · Thommen et al. · 2018 [cited by applicant]
US 20180014000A1 · Blanquart et al. · 2018 [cited by applicant]
US 20180020920A1 · Ermilov et al. · 2018 [cited by applicant]
US 20180038845A1 · Zimmermann et al. · 2018 [cited by applicant]
US 20180217262A1 · Albelo et al. · 2018 [cited by applicant]
US 20180234603A1 · Moore et al. · 2018 [cited by applicant]
US 20180246313A1 · Eshel et al. · 2018 [cited by applicant]
US 20180310828A1 · DiMaio et al. · 2018 [cited by applicant]
US 20190056498A1 · Sonn et al. · 2019 [cited by applicant]
US 20190124247A1 · Behrooz et al. · 2019 [cited by applicant]
US 20190125361A1 · Shelton, IV et al. · 2019 [cited by applicant]
US 20190125454A1 · Stokes et al. · 2019 [cited by applicant]
US 20190129037A1 · Fujita et al. · 2019 [cited by applicant]
US 20190149713A1 · Blanquart et al. · 2019 [cited by applicant]
US 20190191974A1 · Talbert et al. · 2019 [cited by applicant]
US 20190191975A1 · Talbert et al. · 2019 [cited by applicant]
US 20190191976A1 · Talbert et al. · 2019 [cited by applicant]
US 20190191977A1 · Talbert et al. · 2019 [cited by applicant]
US 20190191978A1 · Talbert et al. · 2019 [cited by applicant]
US 20190197712A1 · Talbert et al. · 2019 [cited by applicant]
US 20190200848A1 · McDowall et al. · 2019 [cited by applicant]
US 20190310239A1 · Roblyer et al. · 2019 [cited by applicant]
US 20190353890A1 · Ueda · 2019 [cited by examiner]
US 20200015925A1 · Scheib · 2020 [cited by applicant]
US 20200041417A1 · Bawendi et al. · 2020 [cited by applicant]
US 20200060530A1 · Yabe · 2020 [cited by examiner]
US 20200209401A1 · Motoyama · 2020 [cited by examiner]
US 20200309921A1 · Yasu et al. · 2020 [cited by applicant]
US 20200315439A1 · Mizoguchi et al. · 2020 [cited by applicant]
US 20200359940A1 · Saito et al. · 2020 [cited by applicant]
US 20200397242A1 · Talbert et al. · 2020 [cited by applicant]
US 20200400499A1 · Talbert et al. · 2020 [cited by applicant]
US 20200400500A1 · Talbert et al. · 2020 [cited by applicant]
US 20200400501A1 · Talbert et al. · 2020 [cited by applicant]
US 20200400828A1 · Talbert et al. · 2020 [cited by applicant]
US 20200404171A1 · Talbert et al. · 2020 [cited by applicant]
US 20210106215A1 · Shinji · 2021 [cited by examiner]
US 20210356757A1 · Weigel et al. · 2021 [cited by applicant]
CN 102279048A · 2011 [cited by applicant]
CN 102792124B · 2012 [cited by applicant]
CN 204207717A · 2015 [cited by applicant]
CN 104619237B · 2015 [cited by applicant]
CN 107407597A · 2017 [cited by applicant]
CN 107851176A · 2018 [cited by applicant]
CN 108378825A · 2018 [cited by applicant]
CN 111526775A · 2020 [cited by applicant]
CN 111565620A · 2020 [cited by applicant]
CN 111601536A · 2020 [cited by applicant]
CN 110891511B · 2023 [cited by applicant]
JP H04158205A · 1992 [cited by applicant]
JP 2002315721A · 2002 [cited by applicant]
JP 2006023382A · 2006 [cited by applicant]
JP 2007029232A · 2007 [cited by applicant]
JP 2007163241A · 2007 [cited by applicant]
JP 2008259595A · 2008 [cited by applicant]
JP 2010125284A · 2010 [cited by applicant]
JP 2011206227A · 2011 [cited by applicant]
JP 2011206435A · 2011 [cited by applicant]
JP 2012016545A · 2012 [cited by applicant]
JP 2012019982A · 2012 [cited by applicant]
JP 2012019983A · 2012 [cited by applicant]
JP 2012023492A · 2012 [cited by applicant]
JP 2012105715A · 2012 [cited by applicant]
JP 2012213550A · 2012 [cited by applicant]
JP 2015119712A · 2015 [cited by applicant]
JP 2015119836A · 2015 [cited by applicant]
JP 2015530893A · 2015 [cited by applicant]
JP 2015531271A · 2015 [cited by applicant]
JP 2016007336A · 2016 [cited by applicant]
JP 2016112168A · 2016 [cited by applicant]
JP 2016202726A · 2016 [cited by applicant]
JP 2018042676A · 2018 [cited by applicant]
TW 201725527A · 2017 [cited by applicant]
WO WO2009143491A2 · 2009 [cited by applicant]
WO WO2012066501A1 · 2012 [cited by examiner]
WO WO2012116339A1 · 2012 [cited by applicant]
WO WO2014018951A1 · 2014 [cited by applicant]
WO WO2015016172A · 2014 [cited by applicant]
WO WO2014134314A1 · 2014 [cited by applicant]
WO WO2015077493A1 · 2015 [cited by applicant]
WO WO2014073138A1 · 2016 [cited by applicant]
WO WO2016203572A1 · 2016 [cited by applicant]
WO WO2017066493A1 · 2017 [cited by applicant]
WO WO2017201093A1 · 2017 [cited by applicant]
WO WO2017223206A1 · 2017 [cited by applicant]
WO WO2016185763A · 2018 [cited by applicant]
WO WO2019133736A1 · 2019 [cited by applicant]
WO WO2019133737A1 · 2019 [cited by applicant]
WO WO2019133739A1 · 2019 [cited by applicant]
WO WO2019133741A1 · 2019 [cited by applicant]
WO WO2019133750A1 · 2019 [cited by applicant]
WO WO2019133753A1 · 2019 [cited by applicant]
WO WO2020257027A1 · 2020 [cited by applicant]
WO WO2020257028A1 · 2020 [cited by applicant]
WO WO2020257029A1 · 2020 [cited by applicant]
WO WO2020257030A1 · 2020 [cited by applicant]
WO WO2020257031A1 · 2020 [cited by applicant]
WO WO2020257032A1 · 2020 [cited by applicant]
English Translation of CN102792124 prepared by Google Patents (https://patents.google.com/patent/CN102792124B/en?oq=CN102792124). [cited by applicant]
Translation of CN108378825A prepared by Google Patents (https://patents.google.com/patent/CN108378825A/en?oq=CN108378825). [cited by applicant]
English Translation of CN110891511 prepared by Google Patents (https://patents.google.com/patent/CN110891511A/en?oq=CN110891511). [cited by applicant]
English Translation of CN111526775A prepared by Google Patents (https://patents.google.com/patent/CN111526775A/en?oq=CN111526775). [cited by applicant]
English Translation of CN111565620A Prepared by Google Patents (https://patents.google.com/patent/CN111565620A/en?oq=CN111565620). [cited by applicant]
English Translation of CN111601536A Prepared by Google Patents (https://patents.google.com/patent/CN111601536A/en?oq=CN111601536A). [cited by applicant]
English Translation of JP H04-158205 prepared by Google Patents (https://patents.google.com/patent/JPH04158205A/en?oq=JPH04158205). [cited by applicant]
English Translation of JP2002315721 prepared by Google Patents (https://patents.google.com/patent/JP2002315721A/en?oq=JP2002315721). [cited by applicant]
English Translation of JP2006023382 prepared by Google Patents (https://patents.google.com/patent/JP2006023382A/en?oq=JP2006023382). [cited by applicant]
English translation of JP2007029232 prepared by Google Patents (https://patents.google.com/patent/JP2007029232A/en?oq=JP2007029232). [cited by applicant]
English Translation of JP2008259595 prepared by Google Patents (https://patents.google.com/patent/JP2008259595A/en?oq=JP2008259595). [cited by applicant]
English Translation of JP2010125284 prepared by Google Patents (https://patents.google.com/patent/JP2010125284A/en?oq=JP2010125284). [cited by applicant]
English Translation of JP 2011206227 prepared by Google Patents (https://patents.google.com/patent/JP2011206227A/en?oq=JP2011206227). [cited by applicant]
English translation of JP 2011206435 prepared by Google Patents (https://patents.google.com/patent/JP2011206435A/en?oq=JP2011206435). [cited by applicant]
English Translation of JP 2012016545 prepared by Google Patents (https://patents.google.com/patent/JP2012016545A/en?oq=JP2012016545). [cited by applicant]
English Translation of JP2012019982 prepared by Google Patents (https://patents.google.com/patent/JP2012019982A/en?oq=JP2012019982). [cited by applicant]
English Translation of JP 2012019983 prepared by Google Patents (https://patents.google.com/patent/JP2012019983A/en?oq=JP2012019983). [cited by applicant]
English Translation of JP2012023492 prepared by Google Patents (https://patents.google.com/patent/JP2012023492A/en?oq=JP2012023492). [cited by applicant]
English Translation of JP 2012105715 prepared by Google Patents (https://patents.google.com/patent/JP2012105715A/en?oq=JP2012105715). [cited by applicant]
English Translation of JP2012213550 prepared by Google Patents (https://patents.google.com/patent/JP2012213550A/en?oq=JP2012213550). [cited by applicant]
English Translation of JP2015119712 prepared by Google Patents (https://patents.google.com/patent/JP2015119712A/en?oq=JP2015119712). [cited by applicant]
English Translation of JP2015119836 prepared by Google Patents (https://patents.google.com/patent/JP2015119836A/en?oq=JP2015119836). [cited by applicant]
English translation of JP2015530893 prepared by Google Patents (https://patents.google.com/patent/JP2015530893A/en?oq=JP2015530893). [cited by applicant]
English translation of JP2015531271 prepared by Google Patents (https://patents.google.com/patent/JP2015531271A/en?oq=JP2015531271). [cited by applicant]
English Translation of JP2016007336 prepared by Google Patents (https://patents.google.com/patent/JP2016007336A/en?oq=JP2016007336). [cited by applicant]
English Translation of JP2016202726 prepared by Google Patents (https://patents.google.com/patent/JP2016202726A/en?oq=JP2016202726). [cited by applicant]
English Translation of JP2018042676 prepared by Google Patents (https://patents.google.com/patent/JP2018042676A/en?oq=JP2018042676). [cited by applicant]
English Translation of WO2014073138 prepared by Google Patents (https://patents.google.com/patent/JPWO2014073138A1/en?oq=WO2014073138). [cited by applicant]
English Translation of WO2016203572 prepared by Google Patents (https://patents.google.com/patent/WO2016203572A1/en?oq=WO2016203572). [cited by applicant]
English Translation of Notification of Reasons for Refusal issued by the Japanese Intellectual Property Office on Mar. 14, 2023, in connection with Japanese Patent Application No. 2020-536006. [cited by applicant]
English Translation of Notification of Reasons for Refusal issued by the Japanese Intellectual Property Office on Dec. 6, 2022, in connection with Japanese Patent Application No. 2020-536245. [cited by applicant]
English Translation of Notification of Reasons for Refusal issued by the Japanese Intellectual Property Office on May 5, 2023, in connection with Japanese Patent Application No. 2020-536245. [cited by applicant]
English Translation of Notification of Reasons for Refusal issued by the Japanese Intellectual Property Office on Dec. 4, 2022, in connection with Japanese Patent Application No. 2020-536243. [cited by applicant]
English Translation of Notification of Reasons for Refusal issued by the Japanese Intellectual Property Office on May 5, 2023, in connection with Japanese Patent Application No. 2020-536243. [cited by applicant]
Supplementary European Search Report of EP 20827452.2 dated May 4, 2023. [cited by applicant]
“Paul Dorval:”“Miniaturisation des technologies d'imagerie de fluorescence pour assister la chirurgie mini-invasive”“, Feb. 25, 2015 (Feb. 25, 2015), XP055621190, Retrieved from the Internet: URL:https://tel.archives-ou… [cited by applicant]
“Geng Jason et al:”“Review of 3-D Endoscopic Surface Imaging Techniques”“, IEEE Sensors Journal, IEEE, USA, vol. 14, No. 4, Apr. 1, 2014 (Apr. 1, 2014), pp. 945-960, XP011539779, ISSN: 1530-437X, DOI: 10.1109/JSEN.2013.… [cited by applicant]
“Clancy Neil T. et al:”“Spectrally encoded fiber-based structured lighting probe for intraoperative 3D imaging”“, Biomedical Optics Express, vol. 2, No. 11, Nov. 1, 2011 (Nov. 1, 2011), p. 3119, XP093049327, United Stat… [cited by applicant]
“Lam K. Nguyen and Eli Margalith:”“Rapid, calibrated, high-resolution, hyperspectral imaging using tunable laser source”“, Proc. of SPIE Defense, Security and Sensing, vol. 7319, Apr. 28, 2009 (Apr. 28, 2009), XP0404966… [cited by applicant]
English translation of WO 2017066493 prepared by Google Patents. [cited by applicant]
English translation of CN 102279048A prepared by Google Patents. [cited by applicant]
English translation of CN 107407597A prepared by Google Patents. [cited by applicant]
English translation of CN 204207717U prepared by Google Patents. [cited by applicant]
English translation of JP 2007163241 prepared by Google Patents. [cited by applicant]
English translation of JP 2016112168 prepared by Google Patents. [cited by applicant]
English translation of TW 201725527A prepared by Google Patents. [cited by applicant]
English translation of CN 104619237 prepared by Google Patents on Sep. 10, 2025. [cited by applicant]
English translation of CN 107851176 prepared by Google Patents on Sep. 10, 2025. [cited by applicant]