IP Library › Granted Patent US 12,357,625
Granted Patent B2
US 12,357,625 · App. 17/524,304 · Granted Jul 15, 2025

Methods of regulating oxidoreductase activity for treatment of chronic obstructive pulmonary disease (COPD)

Inventor: Jonnie R. Williams (Sarasota, FL)
Assignee: TNF Pharmaceuticals, Inc.
A61K31/465A61K8/4926A61K31/4439A61P3/08C07K14/4747Y02A50/30
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Quick Facts
Patent No.
US 12,357,625
App. No.
17/524,304
Granted
Jul 15, 2025
Kind
B2
Abstract

In some aspects, a method of regulating oxidoreductase activity for treating an inflammation or age-related disorder involves administering to an individual isomyosmine or a pharmaceutically acceptable salt thereof. In other aspects, a method of treating oxidative stress associated with an inflammation or age-related disorder involves administering to an individual a therapeutically effective amount of isomyosmine or a pharmaceutically acceptable salt thereof. In other aspects, isomyosmine or a pharmaceutically acceptable salt thereof may be administered to an individual for the treatment of infectious or parasitic diseases or various other disorders.

Claims (7)

1. A method of treating chronic obstructive pulmonary disease (COPD) comprising administering to an individual in need thereof a therapeutically effective amount of isomyosmine or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable vehicle therefor.

2. The method of claim 1 , wherein the therapeutically effective amount is from about 0.001 to about 75 mg/kg/day.

3. The method of claim 1 , wherein the therapeutically effective amount is from about 0.01 to about 50 mg/kg/day.

4. The method of claim 1 , wherein the therapeutically effective amount is from about 0.1 to about 40 mg/kg/day.

5. The method of claim 1 , wherein the therapeutically effective amount is from about 1 to about 30 mg/kg/day.

6. The method of claim 1 , wherein the therapeutically effective amount is from about 1 to about 20 mg/kg/day.

7. The method of claim 1 , wherein the therapeutically effective amount is from about 1 to about 10 mg/kg/day.

Assignments (4)
CHANGE OF NAME Recorded Jun 10, 2025
From: MYMD PHARMACEUTICALS, INC.
To: TNF PHARMACEUTICALS, INC.
Reel/Frame 071501/0674 →
MERGER Recorded Apr 22, 2022
From: MYMD PHARMACEUTICALS (FLORIDA), INC.
To: MYMD PHARMACEUTICALS, INC.
Reel/Frame 059680/0941 →
CHANGE OF NAME Recorded Nov 15, 2021
From: MYMD PHARMACEUTICALS, INC.
To: MYMD PHARMACEUTICALS (FLORIDA), INC.
Reel/Frame 058110/0049 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 11, 2021
From: WILLIAMS, JONNIE R.
To: MYMD PHARMACEUTICALS, INC.
Reel/Frame 058088/0984 →
Continuity (6)
Continuation 16928255 · Jul 14, 2020
Continuation In Part 16680677 · Nov 12, 2019
Continuation 15719875 · Sep 29, 2017
Continuation In Part PCTUS2016025126 · Mar 31, 2016
Provisional Application 62140618 · Mar 31, 2015
Related Publication 20220062261A1 · Mar 3, 2022
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