IP Library › Granted Patent US 1,116,151
Granted Patent S1
US 1,116,151 · App. 29/891,241 · Granted Mar 3, 2026

Monolayer

Inventors: Sean Ford (San Diego, CA); Rachel Krupa (San Diego, CA); Eumene Lee (San Diego, CA)
Assignee: Truvian Sciences, Inc.
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Quick Facts
Patent No.
US 1,116,151
App. No.
29/891,241
Granted
Mar 3, 2026
Kind
S1
Claims (1)

The ornamental design for a monolayer as shown and described.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 2, 2023
From: FORD, SEAN; KRUPA, RACHEL; LEE, EUMENE
To: TRUVIAN SCIENCES, INC.
Reel/Frame 064473/0006 →
References Cited (261)
US 4042462A · Johnson et al. · 1977 [cited by applicant]
US 4226531A · Tiffany et al. · 1980 [cited by applicant]
US 4469793A · Guigan · 1984 [cited by applicant]
US 4562570A · Denton · 1985 [cited by applicant]
US 4652137A · Calzi · 1987 [cited by applicant]
US 4656009A · Benajam · 1987 [cited by applicant]
US 4788139A · Ryan · 1988 [cited by applicant]
US 4911642A · Knowles · 1990 [cited by applicant]
US 4990075A · Wogoman · 1991 [cited by applicant]
US 5186844A · Burd et al. · 1993 [cited by applicant]
US D343457S · Stalec · 1994 [cited by examiner]
US 5453359A · Gargan · 1995 [cited by applicant]
US D383215S · Levy · 1997 [cited by examiner]
US 5693233A · Schembri · 1997 [cited by applicant]
US 5888592A · Biallas · 1999 [cited by applicant]
US 6006911A · Levy · 1999 [cited by examiner]
US 6062591A · Ruckdeschel et al. · 2000 [cited by applicant]
US 6143248A · Kellogg et al. · 2000 [cited by applicant]
US 6165795A · Mize · 2000 [cited by examiner]
US 6235531B1 · Kopf-Sill et al. · 2001 [cited by applicant]
US 6302134B1 · Kellogg et al. · 2001 [cited by applicant]
US 6399361B2 · Brotherston et al. · 2002 [cited by applicant]
US 6548788B2 · Kellogg et al. · 2003 [cited by applicant]
US 6563584B1 · Yurrino et al. · 2003 [cited by applicant]
US 6582662B1 · Kellogg et al. · 2003 [cited by applicant]
US 6632399B1 · Kellogg et al. · 2003 [cited by applicant]
US 6637463B1 · Lei et al. · 2003 [cited by applicant]
US 6752961B2 · Kopf-Sill et al. · 2004 [cited by applicant]
US 6811755B2 · McLuen et al. · 2004 [cited by applicant]
US 6818435B2 · Carvalho et al. · 2004 [cited by applicant]
US 6819408B1 · Scrivens et al. · 2004 [cited by applicant]
US D501678S · Oberhardt · 2005 [cited by examiner]
US 6872572B2 · Brady et al. · 2005 [cited by applicant]
US 6935638B2 · Ivanov et al. · 2005 [cited by applicant]
US 7094354B2 · Pugia et al. · 2006 [cited by applicant]
US 7238538B2 · Freitag et al. · 2007 [cited by applicant]
US D598121S · LaStella · 2009 [cited by examiner]
US 7736890B2 · Sia et al. · 2010 [cited by applicant]
US 7790110B2 · Cho et al. · 2010 [cited by applicant]
US 7794849B2 · Lu et al. · 2010 [cited by applicant]
US 7947186B2 · Soares et al. · 2011 [cited by applicant]
US 7991262B2 · Ogawa et al. · 2011 [cited by applicant]
US 7998411B2 · Kopf-Sill et al. · 2011 [cited by applicant]
US 8119393B2 · Qinwei · 2012 [cited by applicant]
US 8212227B2 · Watanabe et al. · 2012 [cited by applicant]
US 8221701B2 · Cho et al. · 2012 [cited by applicant]
US D672050S · Lee et al. · 2012 [cited by applicant]
US 8372357B2 · Andersson et al. · 2013 [cited by applicant]
US D683045S · Domack · 2013 [cited by examiner]
US 8731721B2 · Heiner et al. · 2014 [cited by applicant]
US 8932538B2 · Kim et al. · 2015 [cited by applicant]
US 8945914B1 · Schaff et al. · 2015 [cited by applicant]
US 8962346B2 · Schaff et al. · 2015 [cited by applicant]
US 8969070B2 · Yoo · 2015 [cited by applicant]
US 9108198B2 · Kim et al. · 2015 [cited by applicant]
US 9164091B2 · Kim · 2015 [cited by applicant]
US 9176112B2 · Zhang et al. · 2015 [cited by applicant]
US 9186668B1 · Schaff et al. · 2015 [cited by applicant]
US 9186672B2 · Amasia et al. · 2015 [cited by applicant]
US 9213040B2 · Hwang et al. · 2015 [cited by applicant]
US 9244065B1 · Schaff et al. · 2016 [cited by applicant]
US 9279818B2 · Yoo · 2016 [cited by applicant]
US 9304129B2 · Schaff et al. · 2016 [cited by applicant]
US 9410127B2 · Kim et al. · 2016 [cited by applicant]
US 9421541B2 · Moon et al. · 2016 [cited by applicant]
US 9470609B2 · Wimberger-Friedl et al. · 2016 [cited by applicant]
US 9500579B1 · Sommer et al. · 2016 [cited by applicant]
US 9616424B2 · Lee et al. · 2017 [cited by applicant]
US 9624474B2 · Park · 2017 [cited by applicant]
US 9625916B2 · Da Fonseca et al. · 2017 [cited by applicant]
US 9725792B2 · Ludowise et al. · 2017 [cited by applicant]
US 9726685B2 · Lee et al. · 2017 [cited by applicant]
US 9737889B2 · Moon et al. · 2017 [cited by applicant]
US 9816987B2 · Mehra et al. · 2017 [cited by applicant]
US 9829426B2 · Lee et al. · 2017 [cited by applicant]
US D838380S · Self et al. · 2019 [cited by applicant]
US 10568317B2 · Deshamais et al. · 2020 [cited by applicant]
US D895136S · Whitehead · 2020 [cited by examiner]
US D895141S · Heron · 2020 [cited by examiner]
US D897555S · Chou · 2020 [cited by examiner]
US D915618S · Heron · 2021 [cited by examiner]
US D936856S · Hawkins et al. · 2021 [cited by applicant]
US D954295S · Hawkins et al. · 2022 [cited by applicant]
US D959019S · Hawkins et al. · 2022 [cited by applicant]
US D960386S · Hawkins et al. · 2022 [cited by applicant]
US D968643S · Hawkins et al. · 2022 [cited by applicant]
US 11638918B2 · Kleinemolen et al. · 2023 [cited by applicant]
US 20020031833A1 · Heyneker et al. · 2002 [cited by applicant]
US 20020094147A1 · Herron et al. · 2002 [cited by applicant]
US 20030044992A1 · Chao et al. · 2003 [cited by applicant]
US 20030064004A1 · Agren et al. · 2003 [cited by applicant]
US 20030127609A1 · El-Hage · 2003 [cited by applicant]
US 20030161761A1 · Williams · 2003 [cited by applicant]
US 20030179378A1 · Lafferty · 2003 [cited by applicant]
US 20040009582A1 · Sandall · 2004 [cited by applicant]
US 20040057244A1 · Amano · 2004 [cited by applicant]
US 20040120856A1 · Andersson et al. · 2004 [cited by applicant]
US 20040139455A1 · Ute et al. · 2004 [cited by applicant]
US 20040159343A1 · Shimbara et al. · 2004 [cited by applicant]
US 20040182795A1 · Dorian · 2004 [cited by applicant]
US 20040203136A1 · Kellogg et al. · 2004 [cited by applicant]
US 20050003939A1 · Womer et al. · 2005 [cited by applicant]
US 20050048575A1 · Coassin et al. · 2005 [cited by applicant]
US 20050123445A1 · Blecka · 2005 [cited by applicant]
US 20050136545A1 · Schmid et al. · 2005 [cited by applicant]
US 20050152807A1 · Osterloh et al. · 2005 [cited by applicant]
US 20050229696A1 · Takayama · 2005 [cited by applicant]
US 20050272142A1 · Horita · 2005 [cited by applicant]
US 20060060781A1 · Watanabe et al. · 2006 [cited by applicant]
US 20060160210A1 · Mori et al. · 2006 [cited by applicant]
US 20060223166A1 · Wilding et al. · 2006 [cited by applicant]
US 20060257992A1 · McDevitt et al. · 2006 [cited by applicant]
US 20070010007A1 · Aysta et al. · 2007 [cited by applicant]
US 20070166835A1 · Bobrow et al. · 2007 [cited by applicant]
US 20070190525A1 · Gu et al. · 2007 [cited by applicant]
US 20070298433A1 · Sia et al. · 2007 [cited by applicant]
US 20090123958A1 · Carmon · 2009 [cited by applicant]
US 20090186357A1 · Mauk et al. · 2009 [cited by applicant]
US 20090298092A1 · Tsai et al. · 2009 [cited by applicant]
US 20090298116A1 · Fang · 2009 [cited by applicant]
US 20100055766A1 · Hwang et al. · 2010 [cited by applicant]
US 20100081213A1 · Lee et al. · 2010 [cited by applicant]
US 20100193686A1 · Watanabe et al. · 2010 [cited by applicant]
US 20110038767A1 · Baril · 2011 [cited by applicant]
US 20110086778A1 · Hermann · 2011 [cited by applicant]
US 20110151435A1 · Mehra et al. · 2011 [cited by applicant]
US 20110152202A1 · Du Clos · 2011 [cited by applicant]
US 20110180407A1 · Tyrrell · 2011 [cited by applicant]
US 20110189701A1 · Kim · 2011 [cited by applicant]
US 20110269151A1 · Kim · 2011 [cited by applicant]
US 20110312015A1 · Velaskar · 2011 [cited by applicant]
US 20120041315A1 · Mycek et al. · 2012 [cited by applicant]
US 20120142089A1 · Park · 2012 [cited by applicant]
US 20120200856A1 · Bae · 2012 [cited by applicant]
US 20120202673A1 · Runyon et al. · 2012 [cited by applicant]
US 20120225446A1 · Wimberger-Friedl et al. · 2012 [cited by applicant]
US 20130002753A1 · Wang et al. · 2013 [cited by applicant]
US 20130203634A1 · Jovanovich · 2013 [cited by applicant]
US 20130224568A1 · Fukunago et al. · 2013 [cited by applicant]
US 20130273584A1 · Masci · 2013 [cited by applicant]
US 20130287645A1 · Shaikh et al. · 2013 [cited by applicant]
US 20140017806A1 · Lee · 2014 [cited by applicant]
US 20140138260A1 · Briman · 2014 [cited by applicant]
US 20140185031A1 · Zhang et al. · 2014 [cited by applicant]
US 20140287524A1 · Lee et al. · 2014 [cited by applicant]
US 20140319379A1 · Manian · 2014 [cited by applicant]
US 20140341788A1 · Kim et al. · 2014 [cited by applicant]
US 20150011020A1 · Sundvor · 2015 [cited by applicant]
US 20150064774A1 · Moon et al. · 2015 [cited by applicant]
US 20150079655A1 · Laugharn · 2015 [cited by applicant]
US 20150090674A1 · Lee et al. · 2015 [cited by applicant]
US 20150132753A1 · Ye et al. · 2015 [cited by applicant]
US 20150226652A1 · Jayavanth et al. · 2015 [cited by applicant]
US 20150293097A1 · Godec et al. · 2015 [cited by applicant]
US 20150307927A1 · Nobile · 2015 [cited by applicant]
US 20150321192A1 · Lee · 2015 [cited by applicant]
US 20150360225A1 · Schaff et al. · 2015 [cited by applicant]
US 20150362509A1 · Woodworth · 2015 [cited by applicant]
US 20160038939A1 · Min et al. · 2016 [cited by applicant]
US 20160038940A1 · Babcock · 2016 [cited by applicant]
US 20160040213A1 · Ludowise et al. · 2016 [cited by applicant]
US 20160069919A1 · Holmes · 2016 [cited by applicant]
US 20160279640A1 · Iqbal · 2016 [cited by examiner]
US 20160369323A1 · Revilla · 2016 [cited by examiner]
US 20170023446A1 · Rietveld et al. · 2017 [cited by applicant]
US 20170067871A1 · DeLouise et al. · 2017 [cited by applicant]
US 20170080416A1 · Panetz · 2017 [cited by applicant]
US 20170108494A1 · Mehra et al. · 2017 [cited by applicant]
US 20170120259A1 · Takeuchi · 2017 [cited by applicant]
US 20170151559A1 · Da Fonseca et al. · 2017 [cited by applicant]
US 20170176306A1 · Boehm et al. · 2017 [cited by applicant]
US 20170176481A1 · Accurso · 2017 [cited by applicant]
US 20170304826A1 · Lee et al. · 2017 [cited by applicant]
US 20170354970A1 · Reis et al. · 2017 [cited by applicant]
US 20180038853A1 · Mehra et al. · 2018 [cited by applicant]
US 20180154353A1 · Glezer et al. · 2018 [cited by applicant]
US 20180161772A1 · Rammohan · 2018 [cited by applicant]
US 20180352806A1 · Desharnais et al. · 2018 [cited by applicant]
US 20190162670A1 · Nose et al. · 2019 [cited by applicant]
US 20190300948A1 · Cuppens · 2019 [cited by applicant]
US 20190314813A1 · Doolan · 2019 [cited by applicant]
US 20190388596A1 · Camisani · 2019 [cited by applicant]
US 20200064254A1 · Vanderklein et al. · 2020 [cited by applicant]
US 20200065959A1 · Shartle et al. · 2020 [cited by applicant]
US 20210011001A1 · Chou et al. · 2021 [cited by applicant]
US 20220111385A1 · Yang · 2022 [cited by applicant]
US 20220266242A1 · Samsoonda · 2022 [cited by applicant]
US 20220401959A1 · Emerson et al. · 2022 [cited by applicant]
US 20230132344A1 · Lee · 2023 [cited by applicant]
US 20240139732A1 · Hawkins · 2024 [cited by examiner]
CA 2959410A1 · 2021 [cited by applicant]
CA 3217713A1 · 2024 [cited by applicant]
CN 1206832A · 1999 [cited by applicant]
CN 201298019Y · 2009 [cited by applicant]
CN 1664543B · 2014 [cited by applicant]
CN 110531065A · 2019 [cited by applicant]
CN 211926319U · 2020 [cited by applicant]
DE 19858443A1 · 2000 [cited by applicant]
EM 0150396560001 · 2023 [cited by applicant]
EP 163063A2 · 1985 [cited by applicant]
EP 1542010A1 · 2005 [cited by applicant]
EP 2116305A1 · 2009 [cited by applicant]
EP 2559991A1 · 2023 [cited by applicant]
EP 4382205A2 · 2024 [cited by applicant]
GB 2387642A · 2003 [cited by applicant]
GB 6323497 · 2024 [cited by applicant]
JP 2000011507A · 2000 [cited by applicant]
JP 2003100001A · 2003 [cited by applicant]
JP 2013223441A · 2013 [cited by applicant]
JP 6016168B2 · 2016 [cited by applicant]
KR 3020230009592 · 2024 [cited by examiner]
WO 1995033986A1 · 1995 [cited by applicant]
WO 1999037819A2 · 1999 [cited by applicant]
WO 2005083423A2 · 2005 [cited by applicant]
WO 2005119211A1 · 2005 [cited by applicant]
WO 2009093838A9 · 2009 [cited by applicant]
WO 2011084697A2 · 2011 [cited by applicant]
WO 2011093602A2 · 2011 [cited by applicant]
WO 2011160015A2 · 2011 [cited by applicant]
WO 2014010927A1 · 2014 [cited by applicant]
WO 2014172235A1 · 2014 [cited by applicant]
WO 2016204638A2 · 2016 [cited by applicant]
WO 2016204638A3 · 2017 [cited by applicant]
WO 2017027384A1 · 2017 [cited by applicant]
WO 2017103029A1 · 2017 [cited by applicant]
WO 2017165630A1 · 2017 [cited by applicant]
WO 2017190192A1 · 2017 [cited by applicant]
WO 2017212031A1 · 2017 [cited by applicant]
WO 2018005464A1 · 2018 [cited by applicant]
WO 2018117268A1 · 2018 [cited by applicant]
WO 2018145005A1 · 2018 [cited by applicant]
WO 2019202167A1 · 2019 [cited by applicant]
WO 2020176607A1 · 2020 [cited by applicant]
WO 2020227643A1 · 2020 [cited by applicant]
WO 2021236675A1 · 2021 [cited by applicant]
WO 2021236683A1 · 2021 [cited by applicant]
WO 2022066741A2 · 2022 [cited by applicant]
WO 2022076844A1 · 2022 [cited by applicant]
WO 2022271948A1 · 2022 [cited by applicant]
WO 2024107610 · 2024 [cited by applicant]
WO 2005083423A3 · 2025 [cited by applicant]
US 7,833,478 B2, 11/2010, Andersson (withdrawn) [cited by applicant]
Kartell Microscope Slide Tray. Online, published date unknown. Retrieved on Jan. 28, 2025 from URL: https://www.dynalon.com/PublicStore/product/Kartell-Microscope-Slide-Tray,274,314.aspx. [cited by examiner]
Hawkins, “Rethinking the Clinical Laboratory Test Value Chain: Using New Technologies and New Approaches to Lower Costs, Speed Time-to-Answer, and Contribute to Improved Patient Outcomes,” Truvian Slide Deck pp. 1-19 (A… [cited by applicant]
JP: Decision of Grant in Japanese Patent Application No. 2023-022647 dated Oct. 22, 2024 (4 pages) English Translation. [cited by applicant]
Theranos' Elizabeth Holmes Speaks at AACC Meeting. “Theranos Science & Technology: The Miniaturization of Laboratory Testing,” American Association for Clinical Chemistry [Video] [Screen captures from video retrieved on… [cited by applicant]
CA: Office Action in CA Application No. 225006 dated Feb. 6, 2025 (3 pages). [cited by applicant]
“Red Blood Cell,” Wikipedia (Retrieved from the Internet on Jun. 11, 2020 at https://en.wikipedia.org/wiki/Red_blood_cell) (1987), p. 4. [cited by applicant]
Bond et al., “Drop-to-Drop Variations in the Cellular Components of Fingerprick Blood,” Am. J. Clin. Pathol. 144, pp. 885-894 (2015). [cited by applicant]
CA: Office Action in CA Application No. 225006 dated Oct. 25, 2024 (2 pages). [cited by applicant]
Gale et al., “A review of current Methods in Microfluidic device fabrications and Future commercialization prospects,” 3(60): pp. 1-25 (2018). [cited by applicant]
Giroux et al., “Influence of calcium ions in the flow cytometric analysis of human CD8-positive cells,” 62A(1):61-64 (Nov. 2004) https://doi.org/10.1002/cyto.a.20084. [cited by applicant]
Hauke et al., “An Improved Design and Versatile New Lamination Fabrication Method for Twin Electrode Thin Layer Cells Utilizing Track-etch Membranes”, Electroanalysis, VHC Publishers, Inc, US, 31(1) (2018): pp. 58-65 XP… [cited by applicant]
Kratz et al., “Characterization of four functional biocompatible pressure-sensitive adhesives for rapid prototyping of cell-based lab-on-a-chip and organ-on-a-chip systems,” Scientific Reports 9(1), 9287 (2019) https://… [cited by applicant]
Lassale et al., “Elements of the complete blood count associated with cardiovascular disease incidence: Findings from the EPIC-NL cohort study,” Scientific Reports (2018) 8:3290. [cited by applicant]
Li et al., “Out-of-plane microvalves for whole blood separation on lab-on-a-CD;Out-of-plane microvalves for whole blood separation on lab-on-a-CD”, Journal of Micromechanics & Microengineering, Institute of Physics Publ… [cited by applicant]
Olanrewaju et al., “Capillary microfluidics in microchannels: from microfluidic networks to capillaric circuits”, Lab on a Chip, 18, pp. 2315-2478 (2018) Available on the Internet at URL: https://pubs.rsc.org/en/content… [cited by applicant]
Steigert et al., “Integrated siphon-based metering and sedimentation of whole blood on a hydrophilic lab-on-a-disk”, Biomedical Microdevices, Kluwer Academic Publishers, BO, vol. {0} 9, No. {0} 5, May 16, 2007 (May 16, … [cited by applicant]
Unico “PowerSpin™ DX Centrifuge” (2015). [cited by applicant]
Wörner et al., “Platelet aggregation and the release induced by inophores for divalent cations,” Thrombosis Research 6(4):295-305 (1975). [cited by applicant]
Zhang et al., “A simple statistical parameter for use in evaluation and validation of high throughput screening assays” Journal of Biomolecular Screening 4:67-73 (1999). [cited by applicant]