Granted Patent B2

US 12,210,225 · App. 18/160,200 · Granted Jan 28, 2025

Inventors: Beat Wyss (Niederbipp, CH); Jean-Noel Fehr (Neuchatel, CH); Glenn Noronha (Seattle, WA); Karim Haroud (Villeneuve, CH); Julien Sauvet (Biel, CH); Hans Bernhard (Schliern, CH); Christian Oggenfuss (Lyss, CH); Amitava Gupta (Seattle, WA); Ryo Kubota (Seattle, WA)

Assignee: ACUCELA INC.

G02C7/04G02C7/14G02C11/04G02C2202/24

Abstract

Claims (19)

1. An apparatus to treat myopia of an eye having a retina, comprising:

a lens;

a plurality of light sources; and

a plurality of projection optics coupled to the plurality of light sources to project a plurality of light spots on an outer region of the retina to decrease a progression of myopia of the eye, wherein each of the plurality of projection optics comprises one or more of a mirror, a lens, a diffractive element, a Fresnel lens, a compound Gabor lens, a lightguide, or a wave guide;

wherein the plurality of light spots comprises a plurality of defocused images on the outer region of the retina and wherein said plurality of projection optics is optically coupled to said plurality of light sources to project a plurality of images to a focus anterior to a surface of the retina to form the plurality of defocused images on a plurality of outer regions of the retina;

wherein each of the plurality of projection optics is coupled to a corresponding light source among the plurality of light sources to form an image anterior to an outer portion of the retina and wherein a modulation transfer function of said image decreases by a minimum of 0.1 units for a defocus of 1.0 diopters.

2. The apparatus of claim 1 , wherein said apparatus is configured to reverse myopia.

3. The apparatus of claim 1 , wherein said plurality of projection optics is arranged to project the plurality of light spots from the plurality of light sources at the plurality of outer regions of the retina of the eye with an eccentricity within a range from 15 degrees to 30 degrees with respect to a fovea of the eye.

4. The apparatus of claim 1 , wherein each of said plurality of projection optics is arranged to project an image myopically defocused with respect to a retinal surface, wherein an amount of said defocus is within a range from 2.0D to 5.0D.

5. The apparatus of claim 1 , wherein each of said plurality of projection optics is located 1.5 mm to 5.0 mm from a center of said lens.

6. The apparatus of claim 1 , wherein each of said plurality of light sources has a maximum distance across not exceeding 26 microns.

7. The apparatus of claim 1 , wherein each of the plurality of projection optics has a maximum distance across within a range from 1.5 mm to 200 microns.

8. The apparatus of claim 1 , wherein each of the plurality of projection optics is aspheric and corrected for image aberrations.

9. The apparatus of claim 8 , wherein said each of the plurality of projection optics creates an image anterior to the retina with an image of magnification within a range from 25 to 100.

10. The apparatus of claim 1 , wherein each of the plurality of projection optics comprises a combination of convex and concave mirrors.

11. The apparatus of claim 1 , wherein the plurality of images focused anterior to the outer portion of the retina comprises magnitude of modulation transfer function of no less than 0.75 at a spatial frequency of 10 lp/mm, and no less than 0.40 at a spatial frequency of 50 lp/mm, in order to form the plurality of defocused images on the outer portion of the retina.

12. The apparatus of claim 1 , wherein each of the plurality of projection optics comprises a collimating optic configured to form the image anterior to the retina.

13. The apparatus of claim 1 , wherein each of the plurality of projection optics comprises a single lens to function both as a collimating optic and an image forming optic.

14. The apparatus of claim 1 , wherein said plurality of light sources comprises from 4 to 8 micro-displays, disposed evenly along an arc of said lens, each being displaced equally from an optical center of said lens.

Assignments (1)

Continuity (5)

References Cited (374)