Granted Patent B2

US 12,599,548 · App. 18/732,895 · Granted Apr 14, 2026

Inventors: Tomohiro Hakozaki (Cincinnati, OH); Leo Timothy Laughlin, II (Mason, OH); Matthew Clair Ehrman (Singapore, SG); XiPing Ng (Singapore, SG)

Assignee: The Procter & Gamble Company

A61K8/604A61K8/342A61K8/365A61K8/675A61Q19/08

Abstract

Claims (17)

1 . A skin care composition, comprising:

a) a sucrose ester chosen from sucrose laurate, sucrose dilaurate, sucrose trilaurate, or mixtures thereof;

b) hexyldecanol; and

c) a dermatologically acceptable carrier, wherein the fatty alcohol and sucrose ester are present at a weight ratio of 1:1 to 5:1, based on the weight of the composition, and the combination of sucrose ester and fatty alcohol has a synergy factor of at least 1.1 according to the Oxidative Stress Test.

2 . The skin care composition of claim 1 , wherein the sucrose ester comprises a mixture of sucrose laurate and sucrose dilaurate.

3 . The skin care composition of claim 2 , wherein sucrose laurate is present at about 55% to about 80%, by weight of the sucrose ester and the sucrose dilaurate is present at about 20% to about 45% by weight of the sucrose ester.

4 . The skin care composition of claim 1 , wherein the composition further comprises at least one additional ingredient chosen from vitamins, minerals, peptides, sugar amines, sunscreen agents, oil control agents, flavonoid compounds, anti-oxidants, preservatives, protease inhibitors, tyrosinase inhibitors, anti-inflammatory agents, moisturizing agents, exfoliating agents, skin lightening agents, lubricants, anti-acne actives, chelating agents, anti-wrinkle actives, anti-atrophy actives, phytosterols, N-acyl amino acid compounds, antimicrobials, and antifungals, conditioning agents, emulsifiers, rheology modifiers, or mixtures thereof.

5 . The skin care composition of claim 4 , wherein the additional ingredient is a skin care active chosen from vitamin B3 compounds, undecylenoyl phenylalanine, vitamin E compounds, palmitoylated dipeptides, palmitoylated pentapeptides, vitamin A compounds, or mixtures thereof.

6 . The skin care composition of claim 4 , wherein the composition further comprises a rheology modifier chosen from the group consisting of acrylates/C10-30 alkyl acrylate crosspolymer, acrylates vinyl isodeconate crosspolymers, polyacrylate crosspolymer-6, sodium polyacryloyldimethyl taurate, or mixtures thereof.

7 . The skin care composition of claim 4 , wherein the composition further comprises an emulsifier chosen from glycereth-25 pyrrolidonecarboxylic acid isostearate, PEG-100 stearate, steareth-2, steareth-21, or mixtures thereof.

8 . A method of improving cellular energy levels in skin cells affected by oxidative stress, comprising:

a) identifying a target portion of skin where treatment is desired; and

b) applying the skin care composition of claim 1 .

9 . The method of claim 8 , wherein the sucrose ester and the fatty alcohol are each present at about 0.0001% to about 10%, by weight of the composition.

10 . The method of claim 8 , wherein the fatty alcohol is present at about 0.0001% to about 10%, by weight of the composition.

11 . The method of claim 8 , wherein the target portion of skin exhibits a sign of oxidative stress and the composition is applied over the course of a treatment period.

12 . The method of claim 11 , wherein the treatment period is at least 4 weeks and the composition is applied at least once per day.

Continuity (3)

References Cited (135)