Granted Patent B2

US 12,740,891 · App. 19/554,450 · Granted Sep 22, 2026

Inventors: David Y. Badawi (Glenview, IL); Daniel O'Keeffe (San Francisco, CA); Paul Badawi (Atherton, CA)

Assignee: SIGHT SCIENCES, INC.

A61F9/0008A61F9/0017A61F9/007A61F9/00736A61F9/00781

Abstract

Claims (41)

1 . A method for reducing intraocular pressure of an eye comprising:

advancing a device at least partially through an anterior chamber of the eye and into Schlemm's canal, wherein the device comprises a conduit for delivering viscoelastic fluid to Schlemm's canal;

advancing the conduit along an arc of Schlemm's canal;

delivering about 8 μl to about 50 μl of viscoelastic fluid to Schlemm's canal to dilate associated collector channels; and

tensioning trabecular meshwork of the eye using a suture.

2 . The method of claim 1 , further comprising delivering the suture using an ab interno approach.

3 . The method of claim 1 , wherein the tension does not tear the trabecular meshwork.

4 . The method of claim 1 , further comprising delivering the suture to Schlemm's canal.

5 . The method of claim 1 , wherein the suture stretches the trabecular meshwork.

6 . The method of claim 1 , wherein the viscoelastic fluid is delivered while moving the conduit.

7 . The method of claim 6 , wherein the viscoelastic fluid is delivered while retracting the conduit along the arc of Schlemm's canal.

8 . The method of claim 1 , wherein about 20 μl of viscoelastic fluid is delivered.

9 . The method of claim 1 , wherein the viscoelastic fluid is delivered about at least a 90 degree arc of Schlemm's canal.

10 . The method of claim 1 , wherein delivering the viscoelastic fluid comprises pressurizing a fluid reservoir.

11 . The method of claim 1 , wherein the device further comprises a handle and a cannula coupled to the handle, and wherein the conduit is slidably positioned within the cannula.

12 . The method of claim 11 , wherein the handle further comprises an actuator configured to deliver the viscoelastic fluid.

13 . The method of claim 12 , wherein the handle is capable of being held in a single hand of a user.

14 . A method for reducing intraocular pressure comprising:

advancing a device at least partially through an anterior chamber of an eye and into Schlemm's canal, wherein the device comprises a conduit for delivering viscoelastic fluid to Schlemm's canal;

advancing the conduit along an arc of Schlemm's canal;

delivering about 8 μl of viscoelastic fluid to Schlemm's canal while retracting the conduit; and

tensioning trabecular meshwork of the eye using a suture.

15 . The method of claim 14 further comprising delivering the suture using an ab interno approach.

16 . The method of claim 14 , wherein the tension does not tear the trabecular meshwork.

17 . The method of claim 14 , further comprising delivering the suture to Schlemm's canal.

18 . The method of claim 14 , wherein the suture stretches the trabecular meshwork.

19 . The method of claim 14 , wherein the viscoelastic fluid is delivered about at least a 90 degree arc of Schlemm's canal.

20 . The method of claim 14 , wherein delivering the viscoelastic fluid comprises pressurizing a fluid reservoir in fluid communication with the conduit.

21 . A method for reducing intraocular pressure of an eye comprising:

advancing a device at least partially through an anterior chamber of the eye and into Schlemm's canal, wherein the device is configured to deliver viscoelastic fluid to Schlemm's canal;

delivering about 8 μl to about 50 μl of viscoelastic fluid to Schlemm's canal using the device to dilate associated collector channels; and

advancing a suture into Schlemm's canal, wherein the suture tensions trabecular meshwork of the eye.

22 . The method of claim 21 , wherein the suture comprises a diameter of about 50 microns to about 300 microns.

23 . The method of claim 21 , wherein the suture comprises polypropylene.

24 . The method of claim 21 , wherein the suture comprises a lumen extending therethrough.

25 . The method of claim 21 , wherein the suture maintains patency of the Schlemm's canal.

26 . The method of claim 21 , wherein the suture remains in Schlemm's canal as an implant.

27 . The method of claim 21 , wherein the viscoelastic fluid comprises hyaluronic acid, chondroitin sulfate, cellulose, or salts, derivatives, or mixtures thereof.

28 . The method of claim 21 , wherein the viscoelastic fluid is delivered about at least a 90 degree arc of Schlemm's canal.

29 . The method of claim 21 , wherein delivering the viscoelastic fluid comprises pressurizing a fluid reservoir.

30 . The method of claim 21 , wherein the device comprises a handle, wherein the handle comprises an actuator configured to deliver the viscoelastic fluid.

Assignments (2)

Continuity (13)

References Cited (400)