Granted Patent B2

US 12,498,328 · App. 17/936,764 · Granted Dec 16, 2025

Inventors: Ronald W. Myers (Dublin, OH); Michael E. Moran (Plain City, OH); Chen Feng (Mount Laurel, NJ); Suresh Venkatarayalu (Waxhaw, NC); Moin Shafai (Plano, TX); Adam Dewey McBrady (Dallas, TX)

Assignee: Hand Held Products, Inc.

G01N21/7703G01N2021/7713G01N2021/7779

Abstract

Claims (15)

1 . A sample testing device comprising:

a waveguide cartridge comprising a waveguide, wherein the waveguide comprises at least one reference channel and at least one sample channel;

a reference reservoir connected to the at least one reference channel;

a sample reservoir connected to the at least one sample channel;

a multiport valve connected to an inlet of the waveguide cartridge and configured to provide a plurality of configurations comprising:

a first configuration connecting the inlet of the waveguide cartridge to an outlet of the waveguide cartridge,

a second configuration connecting the inlet of the waveguide cartridge to the at least one reference channel and the at least one sample channel, and

a third configuration connecting the inlet of the waveguide cartridge to each of the reference reservoir and the sample reservoir; and

an imaging component coupled the waveguide and configured to capture interference fringe patterns from the waveguide, wherein the multiport valve is switched to the second configuration from the third configuration based on the interference fringe patterns captured by the imaging component.

2 . The sample testing device of claim 1 , further comprising:

a reservoir that is removably connected to the inlet of the waveguide cartridge.

3 . The sample testing device of claim 2 , wherein the reservoir stores a buffer solution, wherein the sample testing device further comprises:

a pump connected to the reservoir and configured to inject the buffer solution through the inlet of the waveguide cartridge.

4 . The sample testing device of claim 1 , further comprising:

a waste collector removably connected to the outlet of the waveguide cartridge.

Assignments (1)

Continuity (7)

References Cited (380)