Modulating nerves within bone using bone fasteners
Methods of using hardware (e.g., bone screws, anchors or other devices) previously inserted within the body to facilitate energy delivery are disclosed. The energy delivery (e.g., thermal energy) may be used for neuromodulation (such as stimulation or denervation), tissue heating and ablation, curing, and other applications in the spine and non-spine orthopedic locations.
1. A method of treating back pain of a subject, the method comprising:
performing a spinal fusion procedure between two adjacent vertebral bodies;
inserting a distal end of a first pedicle screw within a cancellous bone region of a first vertebral body of the two adjacent vertebral bodies, wherein the first pedicle screw comprises a channel extending along a length of the first pedicle screw;
inserting a first radiofrequency energy delivery device through the channel of the first pedicle screw;
inserting a distal end of a second pedicle screw within the cancellous bone region of the first vertebral body, wherein the second pedicle screw comprises a channel extending along a length of the second pedicle screw;
inserting a second radiofrequency energy delivery device through the channel of the second pedicle screw;
applying radiofrequency energy using the first and second radiofrequency energy delivery devices to conduct heat to the cancellous bone region of the first vertebral body sufficient to ablate a nerve within the cancellous bone region of the first vertebral body.
2. The method of claim 1 , further comprising inserting a distal end of a third pedicle screw within the cancellous bone region of a second vertebral body of the two adjacent vertebral bodies and applying thermal energy through a channel of the third pedicle screw to conduct heat to the cancellous bone region of the second vertebral body sufficient to ablate a nerve within the cancellous bone region of the second vertebral body.
3. The method of claim 1 , wherein the first vertebral body is an L5 vertebra and the second vertebral body is an S1 vertebra.
4. The method of claim 1 , further comprising providing cooling to surrounding tissue through the first radiofrequency energy delivery device.
5. The method of claim 1 , wherein at least one of the first pedicle screw and the second pedicle screw comprises an insulating element along a portion of its length.
6. A method of treating back pain of a subject, the method comprising:
performing a spinal fusion procedure between two adjacent vertebral bodies,
wherein performing the spinal fusion procedure comprises inserting a distal end of a first pedicle screw within a cancellous bone region of a first vertebral body of the two adjacent vertebral bodies,
wherein the first pedicle screw comprises a channel extending along a length of the first pedicle screw;
inserting a first radiofrequency energy delivery device through the channel of the first pedicle screw; and
applying radiofrequency energy using the first radiofrequency energy delivery device to conduct heat to the cancellous bone region of the first vertebral body sufficient to ablate a nerve within the cancellous bone region of the first vertebral body.
7. The method of claim 6 , wherein said performing a spinal fusion procedure between two adjacent vertebral bodies further comprises inserting a distal end of a second pedicle screw within the cancellous bone region of a second vertebral body of the two adjacent vertebral bodies, wherein the second pedicle screw comprises a channel extending along a length of the second pedicle screw.
8. The method of claim 7 , further comprising inserting a second radiofrequency energy delivery device through the channel of the second pedicle screw and applying radiofrequency energy using the second radiofrequency energy delivery device to conduct heat to the cancellous bone region of the second vertebral body sufficient to ablate a nerve within the cancellous bone region of the second vertebral body.
9. The method of claim 8 , wherein the first vertebral body is an L5 vertebra and the second vertebral body is an S1 vertebra.
10. The method of claim 6 , wherein said performing a spinal fusion procedure between two adjacent vertebral bodies further comprises inserting a distal end of a second pedicle screw within the cancellous bone region of the first vertebral body, wherein the second pedicle screw comprises a channel extending along a length of the second pedicle screw.
11. The method of claim 10 , further comprising inserting the first radiofrequency energy delivery device through the channel of the second pedicle screw and applying radiofrequency energy using the first radiofrequency energy delivery device.
12. The method of claim 6 , further comprising providing cooling to surrounding tissue through the first radiofrequency energy delivery device.
13. The method of claim 6 , wherein the first pedicle screw comprises an insulating element along a portion of its length.