Granted Patent B2

US 12,636,499 · App. 18/587,764 · Granted May 26, 2026

Inventors: Kyle Harish Srivastava (Saint Paul, MN); Pramodsingh Hirasingh Thakur (Woodbury, MN); Dat Thanh Huynh (North Hollywood, CA); Bryan Allen Clark (Forest Lake, MN); Jianwen Gu (Richmond, TX)

Assignee: Boston Scientific Neuromodulation Corporation

A61N1/36139A61B5/1118A61B5/6801A61N1/36071A61B5/01A61B5/02028A61B5/021A61B5/024A61B5/02416A61B5/0533A61B5/0816A61B5/1112A61B5/1116A61B5/112A61B5/1121A61B5/318A61B5/369A61B5/389A61B5/4806A61B5/4824A61B2562/0219A61B2562/0223A61B2562/0261A61N1/0529A61N1/0551A61N1/36053A61N1/36057A61N1/36062

Abstract

Claims (52)

1 . A neuromodulation system, comprising:

a sensor circuit, including a physiological sensor configured to sense a physiological signal from a patient, and a motion sensor configured to detect a physical activity pattern of the patient representing a change in physical activity over time; and

a controller circuit configured to:

determine a dissimilarity between the detected physical activity pattern and a baseline physical activity pattern at a baseline state of the patient, the dissimilarity indicative of a change in activity from the baseline state;

determine or adjust a data acquisition protocol including one or more of a duration, a data rate, or a data resolution for collecting data from the physiological signal sensed by the physiological sensor based on the determined dissimilarity, including (i) increasing one or more of the data rate, the data resolution, or the data acquisition duration in response to the dissimilarity exceeding a threshold indicative of a decrease in activity from the baseline state, and (ii) decreasing one or more of the data rate, the data resolution, or the data acquisition duration in response to the dissimilarity falling below the threshold indicative of an increase in activity from the baseline state; and

initiate or adjust a neuromodulation therapy to the patient based at least in part on an analysis of the data collected from the sensed physiological signal in accordance with the determined or adjusted data acquisition protocol.

2 . The neuromodulation system of claim 1 , wherein the data acquisition protocol includes a sampling rate for sampling the sensed physiological signal,

wherein the controller circuit is configured to initiate or adjust the neuromodulation therapy based at least in part on the analysis of the data collected from the sensed physiological signal at the determined or adjusted sampling rate.

3 . The neuromodulation system of claim 2 , wherein the baseline physical activity pattern includes a baseline activity level, and the detected physical activity pattern includes a detected activity level,

wherein the controller circuit is configured to increase the sampling rate when the detected activity level falls below the baseline activity level by a first threshold, and to decrease the sampling rate when the detected activity level exceeds the baseline activity level by a second threshold.

4 . The neuromodulation system of claim 2 , wherein the baseline physical activity pattern includes a baseline rate of change in activity level during a specific time of a day, and the detected physical activity pattern includes a detected rate of change in activity level during the specific time of a day;

wherein the controller circuit is configured to increase the sampling rate when the detected rate of change in activity level falls below the baseline rate of change in activity level by a first threshold, and to decrease the sampling rate when the detected rate of change in activity level exceeds the baseline rate of change in activity level by a second threshold.

5 . The neuromodulation system of claim 1 , wherein the data acquisition protocol includes timing for collecting data from the sensed physiological signal,

wherein the controller circuit is configured to initiate or adjust the neuromodulation therapy based at least in part on the analysis of the data collected from the sensed physiological signal at the determined or adjusted timing.

6 . The neuromodulation system of claim 5 , wherein the timing for collecting the data from the sensed physiological signal includes one or more of a time to initiate the data collection or a duration for sampling data from the sensed physiological signal.

7 . The neuromodulation system of claim 6 , wherein the baseline physical activity pattern includes a baseline activity level, and the detected physical activity pattern includes a detected activity level,

wherein the controller circuit is configured to increase the sampling duration when the detected activity level falls below the baseline activity level by a first threshold, and to decrease the sampling duration when the detected activity level exceeds the baseline activity level by a second threshold.

8 . The neuromodulation system of claim 1 , wherein the data acquisition protocol includes a digitization resolution for digitizing the sensed physiological signal,

wherein the controller circuit is configured to initiate or adjust the neuromodulation therapy based at least in part on the analysis of the digitized physiological signal at the determined or adjusted digitization resolution.

9 . The neuromodulation system of claim 8 , wherein the baseline physical activity pattern includes a baseline activity level, and the detected physical activity pattern includes a detected activity level,

wherein the controller circuit is configured to increase the digitization resolution when the detected activity level falls below the baseline activity level by a first threshold, and to decrease the digitization resolution when the detected activity level exceeds the baseline activity level by a second threshold.

10 . The neuromodulation system of claim 1 , wherein the baseline physical activity pattern corresponds to a baseline state free of pain, and wherein the controller circuit is configured to:

determine a pain score using the data collected from the sensed physiological signal in accordance with the determined or adjusted data acquisition protocol; and

initiate or adjust the neuromodulation therapy based at least in part on the determined pain score to alleviate pain.

11 . The neuromodulation system of claim 1 , wherein the baseline physical activity pattern includes a scheduled activity at a specific time of a day,

wherein the controller circuit is configured to determine or adjust the data acquisition protocol based on the determined dissimilarity indicating whether or not the scheduled activity is missing from the detected physical activity at the specific time of a day.

12 . The neuromodulation system of claim 11 , wherein to determine or adjust the data acquisition protocol, the controller circuit is configured to:

increase one or more of a sampling rate, a sampling duration, or a digitization resolution for sampling the sensed physiological signal when the scheduled activity is absent from the detected physical activity at the specific time of a day; and

decrease one or more of the sampling rate, the sampling duration, or the digitization resolution for sampling the sensed physiological signal when the scheduled activity is present in the detected physical activity at the specific time of a day.

13 . A method of operating a neuromodulation system to provide neuromodulation to a patient, the method comprising:

determining a baseline physical activity pattern at a baseline state of the patient;

detecting a physical activity pattern of the patient using a motion sensor, the physical activity pattern representing a change in physical activity over time;

sensing a physiological signal from the patient using a physiological sensor;

determining a dissimilarity between the detected physical activity pattern and the baseline physical activity pattern, the dissimilarity indicative of a change in activity from the baseline state;

based on the determined dissimilarity, determining or adjusting a data acquisition protocol including one or more of a duration, a data rate, or a data resolution for collecting data from the physiological signal sensed by the physiological sensor using a controller circuit, including (i) increasing one or more of the data rate, the data resolution, or the data acquisition duration in response to the dissimilarity exceeding a threshold indicative of a decrease in activity from the baseline state, and (ii) decreasing one or more of the data rate, the data resolution, or the data acquisition duration in response to the dissimilarity falling below the threshold indicative of an increase in activity from the baseline state; and

via the controller circuit, initiating or adjusting a neuromodulation therapy based at least in part on an analysis of the data collected from the sensed physiological signal in accordance with the determined or adjusted data acquisition protocol.

14 . The method of claim 13 , wherein the data acquisition protocol includes a sampling rate for sampling the sensed physiological signal,

wherein initiating or adjusting the neuromodulation therapy is based at least in part on the analysis of the data collected from the sensed physiological signal at the determined or adjusted sampling rate.

15 . The method of claim 14 , wherein the baseline physical activity pattern includes a baseline activity level, and the detected physical activity pattern includes a detected activity level,

wherein determining or adjusting the data acquisition protocol includes increasing the sampling rate when the detected activity level falls below the baseline activity level by a first threshold, and decreasing the sampling rate when the detected activity level exceeds the baseline activity level by a second threshold.

16 . The method of claim 13 , wherein the data acquisition protocol includes timing for collecting data from the sensed physiological signal,

wherein initiating or adjusting the neuromodulation therapy is based at least in part on the analysis of the data collected from the sensed physiological signal at the determined or adjusted timing.

17 . The method of claim 16 , wherein the baseline physical activity pattern includes a baseline activity level, and the detected physical activity pattern includes a detected activity level,

wherein determining or adjusting the data acquisition protocol includes increasing a sampling duration for sampling the sensed physiological signal when the detected activity level falls below the baseline activity level by a first threshold, and decreasing the sampling duration when the detected activity level exceeds the baseline activity level by a second threshold.

18 . The method of claim 13 , wherein the data acquisition protocol includes a digitization resolution for digitizing the sensed physiological signal,

wherein initiating or adjusting the neuromodulation therapy is based at least in part on the analysis of the digitized physiological signal at the determined or adjusted digitization resolution.

19 . The method of claim 13 , wherein the baseline physical activity pattern corresponds to a baseline state free of pain, the method further includes determining a pain score using the data collected from the sensed physiological signal in accordance with the determined or adjusted data acquisition protocol,

wherein initiating or adjusting the neuromodulation therapy is based at least in part on the determined pain score to alleviate pain.

20 . The method of claim 13 , wherein the baseline physical activity pattern includes a scheduled activity at a specific time of a day,

wherein determining or adjusting the data acquisition protocol includes:

increasing one or more of a sampling rate, a sampling duration, or a digitization resolution for sampling the sensed physiological signal when the scheduled activity is absent from the detected physical activity at the specific time of a day; and

decreasing one or more of the sampling rate, the sampling duration, or the digitization resolution for sampling the sensed physiological signal when the scheduled activity is present in the detected physical activity at the specific time of a day.

Continuity (5)

References Cited (400)