Patent Assignment
Reel/Frame 071721/0025
Security Interest
Recorded: 2025-06-25
Pages: 38
Assignor
REVOLUTION MEDICINES, INC.
Executed: 2025-06-23
Assignee
WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT
50 SOUTH SIXTH STREET, SUITE 1290, MINNEAPOLIS, MINNESOTA, 55402
Covered Properties
(190)
2,5-Disubstituted 3-Methyl Pyrazines and 2,5,6-Trisubstituted 3-Methyl Pyrazines as Allosteric SHP2 Inhibitors
Substituted Pyrazolopyrazines, Imidazopyrazines and [1,2,4]Triazolopyrazines as Allosteric SHP2 Inhibitors
SHP2 Inhibitor Compositions and Methods for Treating Cancer
Application:
19/090,050 →
Solid Forms of {6-[(2-Amino-3-Chloropyridin-4-Yl)Sulfanyl]-3-[(3S,4S)-4-Amino-3-Methyl-2-Oxa-8-Azaspiro[4.5]Decan-8-Yl]-5-Methylpyrazin-2-Yl}Methanol, a SHP2 Inhibitor
Bicyclic Heteroaryl Compounds and Uses Thereof
Application:
19/011,414 →
Publication:
US US20260152516A1
SHP2 Inhibitor Dosing and Methods of Treating Cancer
Application:
17/854,721 →
Publication:
US US20230070338A1
Method for Identifying New Therapeutic Agents
Application:
61/427,626 →
Identifying New Therapeutic Agents
Application:
18/648,723 →
Publication:
US US20250076289A1
Compounds That Participate in Cooperative Binding and Uses Thereof
Application:
62/101,945 →
Compounds That Participate in Cooperative Binding and Uses Thereof
Application:
18/638,943 →
Publication:
US US20250101031A1
Compounds That Participate in Cooperative Binding and Uses Thereof
Application:
62/101,925 →
Compounds That Participate in Cooperative Binding and Uses Thereof
Application:
18/899,370 →
Publication:
US US20250121077A1
Compounds That Participate in Cooperative Binding and Uses Thereof
Application:
62/481,956 →
Compounds That Participate in Cooperative Binding and Uses Thereof
Application:
18/787,714 →
Publication:
US US20250206715A1
Methods and Reagents for Analyzing Protein-Protein Interfaces
Application:
62/235,896 →
Methods and Reagents for Analyzing Protein-Protein Interfaces
Application:
18/593,086 →
Publication:
US US20250085291A1
Methods and Reagents for Analyzing Protein-Protein Interfaces
Application:
62/482,018 →
Methods and Reagents for Analyzing Protein-Protein Interfaces
Application:
18/584,357 →
Publication:
US US20240426833A1
Compounds That Participate in Cooperative Binding and Uses Thereof
Application:
62/894,493 →
Compounds That Participate in Cooperative Binding and Uses Thereof
Application:
62/930,489 →
Compounds That Participate in Cooperative Binding and Uses Thereof
Application:
62/783,816 →
Compounds That Participate in Cooperative Binding and Uses Thereof
Application:
18/184,766 →
Publication:
US US20240139185A1
Covalent Ras Inhibitors and Uses Thereof
Application:
62/940,947 →
Covalent Ras Inhibitors and Uses Thereof
Application:
62/969,415 →
Covalent Ras Inhibitors and Uses Thereof
Application:
63/024,868 →
Covalent Ras Inhibitors and Uses Thereof
Application:
17/825,875 →
Publication:
US US20230100838A1
Ras Inhibitors
Application:
62/930,394 →
Ras Inhibitors
Application:
62/951,763 →
Ras Inhibitors
Application:
63/000,375 →
Ras Inhibitors
Application:
63/043,601 →
Ras Inhibitors
Application:
19/044,266 →
Publication:
US US20250368661A1
Ras Inhibitors
Application:
62/930,355 →
Ras Inhibitors
Application:
62/951,652 →
Ras Inhibitors
Application:
63/000,357 →
Ras Inhibitors
Application:
63/011,636 →
Ras Inhibitors
Application:
63/043,588 →
Ras Inhibitors
Ras Inhibitors
Application:
62/930,406 →
Ras Inhibitors
Application:
62/951,562 →
Ras Inhibitors
Application:
63/000,355 →
Ras Inhibitors
Application:
63/043,523 →
Ras Inhibitors
Application:
18/591,721 →
Publication:
US US20250051306A1
Methods for Delaying, Preventing, and Treating Acquired Resistance to Ras Inhibitors
Application:
63/041,071 →
Methods for Delaying, Preventing, and Treating Acquired Resistance to Ras Inhibitors
Application:
63/062,973 →
Methods for Delaying, Preventing, and Treating Acquired Resistance to Ras Inhibitors
Application:
63/117,417 →
Methods for Delaying, Preventing, and Treating Acquired Resistance to Ras Inhibitors
Application:
63/134,128 →
Methods for Delaying, Preventing, and Treating Acquired Resistance to Ras Inhibitors
Application:
63/192,976 →
Methods for Delaying, Preventing, and Treating Acquired Resistance to Ras Inhibitors
Application:
18/011,454 →
Publication:
US US20230233569A1
Ras Inhibitors
Application:
63/078,802 →
Ras Inhibitors
Application:
63/129,231 →
Ras Inhibitors
Application:
63/184,412 →
Ras Inhibitors
Application:
63/192,775 →
Ras Inhibitors
Ras Inhibitors
Ras Inhibitors
Ras Inhibitors
Application:
19/196,483 →
Publication:
US US20250319187A1
Ras Inhibitors
Application:
19/196,471 →
Publication:
US US20250255964A1
Covalent Ras Inhibitors and Uses Thereof
Application:
63/184,500 →
Covalent Ras Inhibitors and Uses Thereof
Application:
18/501,211 →
Publication:
US US20240262847A1
Ras Inhibitors
Application:
63/184,599 →
Ras Inhibitors
Application:
18/762,805 →
Publication:
US US20250145643A1
Ras Inhibitors
Application:
63/184,618 →
Ras Inhibitors
Application:
19/003,004 →
Publication:
US US20250361245A1
Methods for Inhibiting Ras
Application:
63/192,837 →
Methods for Inhibiting Ras
Application:
18/518,027 →
Publication:
US US20240277796A1
Ras Inhibitors
Application:
63/254,013 →
Ras Inhibitors
Application:
18/947,833 →
Publication:
US US20250074923A1
Ras Inhibitors
Application:
63/298,098 →
Ras Inhibitors
Application:
18/769,009 →
Publication:
US US20250197423A1
Methods for Treating Immune Refractory Lung Cancer
Application:
63/317,649 →
Methods for Treating Immune Refractory Lung Cancer
Application:
18/819,406 →
Publication:
US US20250009753A1
Ras Inhibitors
Application:
63/351,146 →
Ras Inhibitors
Application:
63/455,649 →
Ras Inhibitors
Application:
18/973,320 →
Publication:
US US20250129097A1
Methods of Treating a Ras Related Disease or Disorder
Application:
63/526,781 →
Methods of Treating a Ras Related Disease or Disorder
Application:
63/618,731 →
Methods of Treating a Ras Related Disease or Disorder
Application:
18/771,135 →
Publication:
US US20250041295A1
Methods of Treating a Ras Related Disease or Disorder
Application:
19/219,571 →
Publication:
US US20250345328A1
Methods for Treating Cancer
Application:
63/415,635 →
Composition Comprising a First Ras Inhibitor, Second Ras Inhibitor and a SHP2 Inhibitor for Use in the Treatment of Cancer
Application:
19/120,279 →
Publication:
US US20260144799A1
Compounds, Complexes, and Methods for Their Preparation and of Their Use
Application:
63/424,079 →
Compounds, Complexes, and Methods for Their Preparation and of Their Use
Application:
19/200,842 →
Publication:
US US20250269037A1
Ras Inhibitors
Application:
63/457,859 →
Ras Inhibitors
Application:
63/457,850 →
Ras Inhibitors
Application:
63/611,585 →
Ras Inhibitors
Application:
63/624,178 →
Crystalline Forms of Ras Inhibitors, Compositions Containing the Same, and Methods of Use Thereof
Application:
63/459,290 →
Crystalline Forms of Ras Inhibitors, Compositions Containing the Same, and Methods of Use Thereof
Application:
18/634,034 →
Publication:
US US20240352036A1
Crystalline Forms of Ras Inhibitors, Compositions Containing the Same, and Methods of Use Thereof
Application:
63/459,403 →
Crystalline Forms of Ras Inhibitors, Compositions Containing the Same, and Methods of Use Thereof
Application:
18/634,289 →
Publication:
US US20240352038A1
Synthesis of Ras Inhibitors
Application:
63/459,385 →
Synthesis of Ras Inhibitors
Application:
18/634,246 →
Publication:
US US20240383920A1
Synthesis of Ras Inhibitors
Application:
63/459,435 →
Synthesis of Ras Inhibitors
Application:
18/634,098 →
Publication:
US US20240368190A1
Compositions for Inducing Ras Gtp Hydrolysis and Uses Thereof in Combination with Ras(Off) Inhibitors
Application:
63/455,672 →
Compositions for Inducing Ras Gtp Hydrolysis and Uses Thereof
Application:
63/528,255 →
Combination Therapy for a Ras Related Disease or Disorder
Application:
63/464,023 →
Combination Therapy for a Ras Related Disease or Disorder
Application:
63/545,097 →
Combination Therapy for a Ras Related Disease or Disorder
Application:
63/551,254 →
Ras Inhibitors
Application:
63/469,283 →
Methods of Treating a Ras Protein-Related Disease or Disorder
Application:
63/531,175 →
Methods of Treating a Ras Protein-Related Disease or Disorder
Application:
63/543,420 →
Methods of Treating a Ras Protein-Related Disease or Disorder
Application:
63/618,783 →
Methods of Treating a Ras Protein-Related Disease or Disorder
Application:
18/795,852 →
Publication:
US US20250049810A1
Synthesis of Ras Inhibitors
Application:
63/542,112 →
Synthesis of Ras Inhibitors
Application:
63/560,883 →
Synthesis of Ras Inhibitors
Application:
18/904,234 →
Publication:
US US20250115551A1
Methods of Treating a Ras Protein-Related Disease or Disorder
Application:
63/710,296 →
Methods of Treating a Ras Protein-Related Disease or Disorder
Application:
63/794,157 →
Ras Inhibitors
Application:
63/543,841 →
Ras Inhibitors
Application:
63/611,600 →
Ras Inhibitors
Application:
63/638,805 →
Ras Inhibitors
Application:
18/913,242 →
Publication:
US US20250154171A1
Ras Inhibitors
Application:
63/551,943 →
Ras Inhibitors
Application:
63/743,449 →
Peptide Conjugates
Application:
63/575,095 →
Peptide Conjugates
Application:
63/575,310 →
Methods for Predicting Response to a Ras(on) Inhibitor and Combination Therapies
Application:
63/631,881 →
Ras Inhibitors
Application:
63/648,875 →
Ras Inhibitors
Application:
63/736,143 →
Ras Inhibitors
Application:
63/790,944 →
Synthesis of Ras Inhibitors
Application:
63/700,982 →
Ras Inhibitors
Application:
63/733,538 →
Methods of Treating a Ras Protein-Related Disease or Disorder
Application:
63/657,527 →
Methods of Treating a Ras Protein-Related Disease or Disorder
Application:
63/662,775 →
Methods of Treating a Ras Protein-Related Disease or Disorder
Application:
19/230,256 →
Publication:
US US20250375445A1
Ras Inhibitors
Application:
63/665,587 →
Ras Inhibitors
Application:
63/698,358 →
Ras Inhibitors
Application:
63/772,107 →
Ras Inhibitors
Application:
63/816,145 →
Synthesis of Ras Inhibitors
Application:
63/743,017 →
Therapeutic Compositions and Methods
Application:
63/662,756 →
Methods of Treating a Ras Related Disease or Disorder
Application:
63/670,191 →
Methods of Treating a Ras Related Disease or Disorder
Application:
63/670,221 →
Methods of Treating a Ras Related Disease or Disorder
Application:
63/670,216 →
Use of Ras Inhibitor for Treating Pancreatic Cancer
Application:
63/670,510 →
Use of Ras Inhibitor for Treating Pancreatic Cancer
Application:
63/680,332 →
Use of Ras Inhibitor for Treating Pancreatic Cancer
Application:
63/709,147 →
Use of Ras Inhibitor for Treating Pancreatic Cancer
Application:
63/763,098 →
Ras Inhibitors
Application:
63/688,562 →
Compositions and Methods for Treating Lung Cancer
Application:
63/699,441 →
Synthesis of Ras Inhibitors
Application:
63/705,811 →
Synthesis of Ras Inhibitors
Application:
63/736,868 →
Ras Inhibitors
Application:
63/709,587 →
Use of Ras Inhibitors for Treating Cancer
Application:
63/710,273 →
Use of Ras Inhibitors for Treating Cancer
Application:
63/761,346 →
Use of Ras Inhibitors for Treating Cancer
Application:
63/794,110 →
Ras Inhibitors
Application:
63/719,536 →
Ras Inhibitors
Application:
63/723,453 →
Ras Inhibitors
Application:
63/728,977 →
Ras Inhibitors
Application:
63/750,145 →
Ras Inhibitors
Application:
63/806,163 →
C40-, C28-, and C-32-Linked Rapamycin Analogs as mTOR Inhibitors
C26-Linked Rapamycin Analogs as Mtor Inhibitors
Synthesis of Rapamycin Analog Compounds
Application:
18/377,670 →
Publication:
US US20240174615A1
Methods of Treating Cancer with an Mtor Inhibitor
Methods of Treating Cancer with an Mtor Inhibitor
Application:
18/886,780 →
Publication:
US US20250114364A1
Use of SOS1 Inhibitors with Mtor Inhibitors to Treat Cancers
Application:
18/559,932 →
Publication:
US US20250134891A1
SHP2 Inhibitor Compositions and Methods for Treating Cancer
Application:
18/655,511 →
Publication:
US US20250090532A1
2,5-Disubstituted 3-Methyl Pyrazines and 2,5,6-Trisubstituted 3-Methyl Pyrazines as Allosteric SHP2 Inhibitors
2,5-Disubstituted 3-Methyl Pyrazines and 2,5,6-Trisubstituted 3-Methyl Pyrazines as Allosteric SHP2 Inhibitors
Substituted Pyrazolopyrazines, Imidazopyrazines and [1,2,4]Triazolopyrazines as Allosteric SHP2 Inhibitors
SHP2 Inhibitor Compositions and Methods for Treating Cancer
Solid Forms of {6-[(2-Amino-3-Chloropyridin-4-Yl)Sulfanyl]-3-[(3S,4S)-4-Amino-3-Methyl-2-Oxa-8-Azaspiro[4.5]Decan-8-Yl]-5-Methylpyrazin-2-Yl}Methanol, a SHP2 Inhibitor
Bicyclic Heteroaryl Compounds and Uses Thereof
Patent:
11,168,102 →
Application:
17/133,340 →
Bicyclic Heteroaryl Compounds and Uses Thereof
Identifying New Therapeutic Agents
Patent:
9,428,845 →
Application:
13/337,875 →
Identifying New Therapeutic Agents
Identifying New Therapeutic Agents
Identifying New Therapeutic Agents
Compounds That Participate in Cooperative Binding and Uses Thereof
Compounds That Participate in Cooperative Binding and Uses Thereof
Compounds That Participate in Cooperative Binding and Uses Thereof
Compounds That Participate in Cooperative Binding and Uses Thereof
Methods and Reagents for Analyzing Protein-Protein Interfaces
Methods and Reagents for Analyzing Protein-Protein Interfaces
Methods and Reagents for Analyzing Protein-Protein Interfaces
Ras Inhibitors
Ras Inhibitors
Ras Inhibitors
Ras Inhibitors
Ras Inhibitors
Ras Inhibitors
Ras Inhibitors
Ras Inhibitors
C40-, C28-, and C-32-Linked Rapamycin Analogs as mTOR Inhibitors
Patent:
10,980,889 →
Application:
16/831,579 →
C40-, C28-, and C-32-Linked Rapamycin Analogs as mTOR Inhibitors
C40-, C28-, and C-32-Linked Rapamycin Analogs as mTOR Inhibitors
C26-Linked Rapamycin Analogs as Mtor Inhibitors
Methods of Treating Cancer with an Mtor Inhibitor
Related Assignments
(25)
Other recorded transfers of the patents in this record — the chain of ownership.
Assignment of Assignor's Interest
Apr 14, 2015
From: VERDINE, GREGORY LAWRENCE; BOWMAN, BRIAN ROGER; SOWA, MATHEW EDWARD; BLODGETT, JOSHUA ALAN VAN DYKE
To: WARP DRIVE BIO, LLC
Reel/Frame 035405/0808 →
Assignment of Assignor's Interest
Apr 14, 2015
From: VERDINE, GREGORY LAWRENCE; NICHOLS, MATTHEW JAMES; STILES, DYLAN TALBOT; ANTHONY, NEVILLE JOHN
To: WARP DRIVE BIO, LLC
Reel/Frame 035406/0374 →
Assignment of Assignor's Interest
Nov 6, 2015
From: VERDINE, GREGORY L.; NICHOLS, M. JAMES; TOWNSON, SHARON A.; SHIGDEL, UDDHAV KUMAR
To: WARP DRIVE BIO, LLC
Reel/Frame 036976/0893 →
Change of Name
Mar 8, 2016
From: WARP DRIVE BIO, LLC
To: WARP DRIVE BIO, INC.
Reel/Frame 038040/0639 →
Corrective Assignment to Correct the Nature of Conveyance Previously Recorded on Reel 038040 Frame 0639. Assignor(S) Hereby Confirms the Certificate of Incorporation.
Apr 5, 2016
From: WARP DRIVE BIO, INC.
To: WARP DRIVE BIO, INC.
Reel/Frame 038361/0533 →
Certificate of Merger
Apr 5, 2016
From: WARP DRIVE BIO, LLC
To: WARP DRIVE BIO, INC.
Reel/Frame 038358/0586 →
Assignment of Assignor's Interest
Jul 18, 2018
From: MULVIHILL, MARK J.; JIN, MEIZHONG
To: WARP DRIVE BIO, INC.
Reel/Frame 046380/0364 →
Assignment of Assignor's Interest
Jul 18, 2018
From: MULVIHILL, MARK JOSEPH; JIN, MEIZHONG
To: WARP DRIVE BIO, INC.
Reel/Frame 046571/0028 →
Assignment of Assignor's Interest
Aug 21, 2018
From: PERL, NICHOLAS
To: WARP DRIVE BIO, INC.
Reel/Frame 046650/0063 →
Change of Name
Nov 14, 2018
From: WARP DRIVE BIOSYNTHETICS
To: WARP DRIVE BIO, LLC
Reel/Frame 047536/0104 →
Assignment of Assignor's Interest
Mar 15, 2019
From: JIN, MEIZHONG; PERL, NICHOLAS; KOHLMANN, ANNA; YIN, NING
To: WARP DRIVE BIO, INC.
Reel/Frame 048609/0761 →
Assignment of Assignor's Interest
Apr 3, 2019
From: KOLTUN, ELENA S.; GILL, ADRIAN L.
To: REVOLUTION MEDICINES, INC.
Reel/Frame 048778/0465 →
Assignment of Assignor's Interest
Sep 24, 2019
From: WARP DRIVE BIO, INC.
To: REVOLUTION MEDICINES, INC.
Reel/Frame 050473/0976 →
Assignment of Assignor's Interest
Nov 4, 2019
From: JIN, MEIZHONG; PERL, NICHOLAS; YIN, NING; AHN, JAE YOUNG
To: WARP DRIVE BIO, INC.
Reel/Frame 050902/0350 →
Assignment of Assignor's Interest
Nov 4, 2019
From: KOHLMANN, ANNA; LOWE, JASON T.; MULVIHILL, MARK JOSEPH
To: WARP DRIVE BIO, INC.
Reel/Frame 050902/0418 →
Assignment of Assignor's Interest
Nov 19, 2019
From: KOLTUN, ELENA S.; GILL, ADRIAN L.
To: REVOLUTION MEDICINES, INC.
Reel/Frame 051050/0231 →
Assignment of Assignor's Interest
Nov 26, 2019
From: WARP DRIVE BIO, INC.
To: REVOLUTION MEDICINES, INC.
Reel/Frame 051114/0988 →
Assignment of Assignor's Interest
Dec 13, 2019
From: KOLTUN, ELENA S.; GILL, ADRIAN L.
To: REVOLUTION MEDICINES, INC.
Reel/Frame 051278/0780 →
Assignment of Assignor's Interest
Dec 13, 2019
From: JIN, MEIZHONG; PERL, NICHOLAS; YIN, NING; AHN, JAE YOUNG
To: WARP DRIVE BIO, INC.
Reel/Frame 051277/0925 →
Assignment of Assignor's Interest
Dec 13, 2019
From: KOHLMANN, ANNA; LOWE, JASON T.; MULVIHILL, MARK JOSEPH
To: WARP DRIVE BIO, INC.
Reel/Frame 051278/0405 →
Assignment of Assignor's Interest
Dec 13, 2019
From: WARP DRIVE BIO, INC.
To: REVOLUTION MEDICINES, INC.
Reel/Frame 051278/0919 →
Assignment of Assignor's Interest
Dec 17, 2019
From: KOLTUN, ELENA S.; CREGG, JAMES; AAY, NAING; BUCKL, ANDREAS
To: REVOLUTION MEDICINES, INC.
Reel/Frame 051302/0847 →
Assignment of Assignor's Interest
Dec 30, 2019
From: PITZEN, JENNIFER; AGGEN, JAMES; BURNETT, G. LESLIE; GILL, ADRIAN L.
To: REVOLUTION MEDICINES, INC.
Reel/Frame 051388/0592 →
Assignment of Assignor's Interest
Feb 27, 2020
From: KOLTUN, ELENA S.; CREGG, JAMES; AAY, NAING; BUCKL, ANDREAS
To: REVOLUTION MEDICINES, INC.
Reel/Frame 051947/0387 →
Assignment of Assignor's Interest
Feb 27, 2020
From: WHALEN, DANIEL M.
To: REVOLUTION MEDICINES, INC.
Reel/Frame 051946/0044 →