IP Library › Granted Patent US 12,539,115
Granted Patent B2
US 12,539,115 · App. 17/718,838 · Granted Feb 3, 2026

System of surgical staple cartridges comprising absorbable staples

Inventors: Jason L. Harris (Lebanon, OH); Chad E. Eckert (Terrace Park, OH); Mark H. Ransick (West Chester, OH); William J. K. Crone (Newcastle upon Tyne, GB); Stephen R. Lovelock (Cambridge, GB); Haruka Kobayashi (Cambridge, GB); Richard T. Bown (Cambridge, GB); Richard J. Andrews (Cambridge, GB); Sophie K. Trott (Cheltenham, GB); Ailsa G. Bradbury (Cambridge, GB); Howell T. Goldrein (Cambridge, GB); Shashi S. Pathak (Mason, OH); Jason M. Rector (Maineville, OH); Michael J. Vendely (Lebanon, OH); Shannon L. Jones (Cincinnati, OH); Ryan W. McGhee (Cincinnati, OH); Frederick E. Shelton, IV (Hillsboro, OH)
Assignee: CILAG GMBH INTERNATIONAL
A61B17/0644A61B17/064A61B17/072A61B17/07207A61B17/105A61B50/3001A61B90/98A61L31/022A61L31/028A61L31/042A61L31/048A61L31/10A61L31/148A61L31/16A61B2017/00004A61B2017/00022A61B2017/00084A61B2017/00119A61B2017/00845A61B17/0686A61B2017/0688A61B2017/07228A61B2017/07235A61B2017/07257A61B2017/07264A61B2017/07271A61B2017/07278A61B2017/07285A61B2050/3004A61B2090/0807
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Quick Facts
Patent No.
US 12,539,115
App. No.
17/718,838
Granted
Feb 3, 2026
Kind
B2
Abstract

Staple cartridges including bioabsorbable staples are disclosed. The staples are configured such that they are bioabsorbable within a desired time frame.

Claims (39)

1 . A staple cartridge, comprising:

a deck;

an elongate slot;

staple cavities defined in said deck; and

staples positioned in said staple cavities, wherein said staples are configured to be deployed into a tissue environment, wherein said staples are comprised of a magnesium-based alloy, and wherein said magnesium-based alloy is selected such that said staples bio-corrode in said tissue environment within a predetermined bio-corrosion timeframe,

wherein said staples comprise a coating, the coating configured to tune a rate of bio-corrosion of the staples to meet the predetermined bio-corrosion timeframe based on a mechanism of action, by balancing an increase of the rate of bio-corrosion caused by the magnesium-based alloy and a decrease of the rate of bio-corrosion caused by a calcification.

2 . The staple cartridge of claim 1 , wherein said coating is applied at manufacture.

3 . The staple cartridge of claim 1 , wherein said staples are configured to be coated after said staples have been deployed into the tissue environment.

4 . The staple cartridge of claim 1 , wherein said coating is further configured to trap ions.

5 . The staple cartridge of claim 1 , wherein said coating is further configured to inhibit onset of oxidation.

6 . The staple cartridge of claim 1 , wherein said coating is further configured to divert deposition therefrom.

7 . The staple cartridge of claim 1 , wherein said coating is further configured to capture deposition thereon.

8 . The staple cartridge of claim 1 , wherein said mechanism of action comprises at least one of oxidation, hydrolysis, galvanic corrosion, a replacement reaction between magnesium and hydrochloric acid, or stress corrosion, and tuning the rate of bio-corrosion comprising at least one of increase, decease, or reserve the rate of bio-corrosion of the staples.

9 . A staple cartridge, comprising:

a deck;

an elongate slot;

staple cavities defined in said deck; and

staples positioned in said staple cavities, wherein said staples are configured to be deployed into a tissue environment, wherein said staples are comprised of a zinc-based alloy, and wherein said zinc-based alloy is selected such that said staples bio-corrode in said tissue environment within a predetermined bio-corrosion timeframe,

wherein said staples comprise a coating, the coating configured to tune a rate of bio-corrosion of the staples to meet the predetermined bio-corrosion timeframe based on a mechanism of action, by balancing an increase of the rate of bio-corrosion caused by the zinc-based alloy and a decrease of the rate of bio-corrosion caused by a calcification.

10 . The staple cartridge of claim 9 , wherein said coating is applied at manufacture.

11 . The staple cartridge of claim 9 , wherein said staples are configured to be coated after said staples have been deployed into the tissue environment.

12 . The staple cartridge of claim 9 , wherein said coating is further configured to trap ions.

13 . The staple cartridge of claim 9 , wherein said coating is further configured to inhibit onset of oxidation.

14 . The staple cartridge of claim 9 , wherein said coating is further configured to divert deposition therefrom.

15 . The staple cartridge of claim 9 , wherein said coating is further configured to capture deposition thereon.

16 . The staple cartridge of claim 9 , wherein said mechanism of action comprises at least one of oxidation, hydrolysis, galvanic corrosion, a replacement reaction between magnesium and hydrochloric acid, or stress corrosion, and tuning the rate of bio-corrosion comprising at least one of increase, decease, or reserve the rate of bio-corrosion of the staples.

17 . A staple cartridge, comprising:

a deck;

an elongate slot;

staple cavities defined in said deck; and

staples positioned in said staple cavities, wherein said staples are configured to be deployed into a tissue environment, wherein said staples are comprised of an iron-based alloy, and wherein said iron-based alloy is selected such that said staples bio-corrode in said tissue environment within a predetermined bio-corrosion timeframe,

wherein said staples comprise a coating, the coating configured to tune a rate of bio-corrosion of the staples to meet the predetermined bio-corrosion timeframe based on a mechanism of action, by balancing an increase of the rate of bio-corrosion caused by the iron-based alloy and a decrease of the rate of bio-corrosion caused by a calcification.

18 . The staple cartridge of claim 17 , wherein said coating is applied at manufacture.

19 . The staple cartridge of claim 17 , wherein said staples are configured to be coated after said staples have been deployed into the tissue environment.

20 . The staple cartridge of claim 17 , wherein said coating is further configured to trap ions.

21 . The staple cartridge of claim 17 , wherein said coating is further configured to inhibit onset of oxidation.

22 . The staple cartridge of claim 17 , wherein said coating is further configured to divert deposition therefrom.

23 . The staple cartridge of claim 17 , wherein said coating is further configured to capture deposition thereon.

24 . The staple cartridge of claim 17 , wherein said mechanism of action comprises at least one of oxidation, hydrolysis, galvanic corrosion, a replacement reaction between magnesium and hydrochloric acid, or stress corrosion, and tuning the rate of bio-corrosion comprising at least one of increase, decease, or reserve the rate of bio-corrosion of the staples.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 7, 2022
From: HARRIS, JASON L.; ECKERT, CHAD E.; RANSICK, MARK H.; PATHAK, SHASHI S.; RECTOR, JASON M.; VENDELY, MICHAEL J.; JONES, SHANNON L.; MCGHEE, RYAN W.; SHELTON, FREDERICK E., IV
To: CILAG GMBH INTERNATIONAL
Reel/Frame 060126/0648 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 7, 2022
From: CRONE, WILLIAM J. K.; LOVELOCK, STEPHEN R.; KOBAYASHI, HARUKA; BOWN, RICHARD T.; ANDREWS, RICHARD J.; TROTT, SOPHIE K.; BRADBURY, AILSA G.; GOLDREIN, HOWELL T.
To: INNOVIA TECHNOLOGY LTD
Reel/Frame 060126/0759 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 7, 2022
From: INNOVIA TECHNOLOGY LTD
To: CILAG GMBH INTERNATIONAL
Reel/Frame 060126/0823 →
Continuity (2)
Provisional Application 63186519 · May 10, 2021
Related Publication 20220354486A1 · Nov 10, 2022
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