Granted Patent B2

US 12,529,696 · App. 18/156,221 · Granted Jan 20, 2026

Inventors: Suresh Venkatarayalu (Waxhaw, NC); Chen Feng (Mount Laurel, NC)

Assignee: Hand Held Products, Inc.

G01N33/531G01N21/17G01N2021/1765G01N2021/416G01N2021/432G01N2021/458

Abstract

Claims (12)

1 . A method for sample testing comprising:

injecting a sample mixture comprising a reference substance and a sample substance to each of a plurality of sample channels and at least one positive reference channel;

generating a plurality of test signals based on interference fringe patterns from the plurality of sample channels and at least one reference signal based on at least one interference fringe pattern from the at least one positive reference channel;

receiving the plurality of test signals associated with the plurality of sample channels and the at least one reference signal from the at least one positive reference channel;

recording the at least one reference signal as at least one positive indication benchmark; and

determining whether each test signal provides a positive indication according to the at least one positive indication benchmark.

2 . The method of claim 1 , further comprising:

in response to determining that a test signal from a sample channel provides a positive indication, generating a candidate data set comprising sample types that match the test signal associated with an antibody mixture coated on the sample channel, wherein the antibody mixture is specific to the sample types in the candidate data set.

3 . The method of claim 1 , further comprising:

in response to determining that a test signal from a sample channel does not provide a positive indication, generating an elimination data set comprising sample types that do not match the test signal associated with an antibody mixture coated on the sample channel, wherein the antibody mixture is not specific to the sample types in the elimination data set.

4 . The method of claim 1 , further comprising:

determining that the sample substance is associated with a sample type that is in each candidate data set and not in any elimination data set.

Assignments (1)

Continuity (10)

References Cited (382)