Measuring tissue proximity for multi-electrode catheter
A system includes a catheter and a processor. The catheter includes a distal-end assembly coupled to a distal end of a shaft for insertion into a cavity of an organ of a patient, the distal-end assembly including (i) one or more functional electrodes configured to be placed in contact with wall tissue of the cavity and (ii) a reference electrode configured to be placed in the cavity but not in contact with the wall tissue. The processor is configured to (i) estimate one or more impedances between one or more of the functional electrodes and the reference electrode, and (ii) based on the impedances, determine, for at least a functional electrode from among the one or more functional electrodes, whether the functional electrode is in physical contact with the wall tissue.
1 . A system, comprising:
a catheter comprising a distal-end assembly coupled to a distal end of a shaft for insertion into a cavity of an organ of a patient, the distal-end assembly comprising (i) a plurality of functional electrodes positioned at one or more corresponding distances from a longitudinal axis of the distal-end assembly and configured to be placed in contact with wall tissue of the cavity and (ii) a reference electrode positioned on an interior portion of the distal-end assembly located along the longitudinal axis and configured to be placed in the cavity but not in contact with the wall tissue of the cavity; and
a processor, which is configured to:
estimate a first impedance value of a plurality of impedance values between a first functional electrode of the plurality of functional electrodes and the reference electrode, the first functional electrode being submerged in blood;
estimate a second impedance value of the plurality of impedance values between a second functional electrode of the plurality functional electrodes and the reference electrode, the second functional electrode being in contact with the wall tissue of the cavity;
estimate a third impedance value of the plurality of impedance values between a third functional electrode of the plurality of functional electrodes and the reference electrode, the third functional electrode selected from remaining functional electrodes of the plurality of functional electrodes in various levels of proximity to the wall tissue of the cavity;
generate a graph, based at least in part on the first impedance value and the second impedance value, that illustrates a relationship between the third impedance value and a distance between the third functional electrode and the wall tissue of the cavity; and
based on the generated graph, determine, for at least the third functional electrode, whether the third functional electrode is in physical contact with the wall tissue of the cavity.
2 . The system according to claim 1 , further comprising a relay assembly that is configured to switch, under control of the processor, between (i) a first configuration for measuring impedances between the plurality of functional electrodes and the reference electrode, and (ii) a second configuration for performing a medical procedure using the plurality of functional electrodes.
3 . The system according to claim 1 , wherein the processor is configured to determine that at least one of the plurality of functional electrodes is in physical contact with the wall tissue by determining that a measured impedance is lower than a prespecified impedance threshold.
4 . The system according to claim 3 , wherein the prespecified impedance threshold is measured while the reference electrode is in contact with blood in the cavity.
5 . The system according to claim 1 , wherein the distal-end assembly comprises an expandable frame comprising multiple splines, wherein each spline of the multiple splines comprises at least one functional electrode of the plurality of functional electrodes.
6 . The system according to claim 5 , wherein each spline of the multiple splines converges distally toward a distal-most point of the expandable frame.
7 . The system according to claim 1 , the distal-end assembly further comprising a center member extending along the longitudinal axis of the catheter, the reference electrode being disposed along the center member.
8 . The system according to claim 7 , the center member further comprising a contraction wire connected to the distal end of the distal-end assembly, the contraction wire configured to cause an expandable frame of the distal-end assembly to expand or contract when pulled.
9 . A method, comprising:
inserting into a cavity of an organ of a patient a catheter comprising a distal-end assembly coupled to a distal end of a shaft, the distal-end assembly comprising (i) a plurality of functional electrodes positioned one or more corresponding distances from a longitudinal axis of the distal-end assembly and configured to be placed in contact with wall tissue of the cavity and (ii) a reference electrode positioned on an interior portion of the distal-end assembly located along the longitudinal axis and configured to be placed in the cavity but not in contact with the wall tissue of the cavity;
estimating a first impedance value of a plurality of impedance values between a first functional electrode of the plurality of functional electrodes and the reference electrode, the first functional electrode being submerged in blood;
estimating a second impedance value of the plurality of impedance values between a second functional electrode of the plurality functional electrodes and the reference electrode, the second functional electrode being in contact with the wall tissue of the cavity;
estimating a third impedance value of the plurality of impedance values between a third functional electrode and the reference electrode, the third functional electrode selected from remaining functional electrodes of the plurality of functional electrodes in various levels of proximity to the wall tissue of the cavity;
generating a graph, based at least in part on the first impedance value and the second impedance value, that illustrates a relationship between the third impedance value and a distance between the third functional electrode and the wall tissue of the cavity; and
based at least in part on the generated graph, determining, for at least the third functional electrode, whether the third functional electrode is in physical contact with the wall tissue of the cavity.
10 . The method according to claim 9 , wherein the distal end assembly comprises an expandable frame comprising multiple splines, wherein each spline of the multiple splines comprises at least one functional electrode of the plurality of functional electrodes.
11 . The method according to claim 9 , further comprising switching between (i) a first configuration for measuring impedances between the plurality of functional electrodes and the reference electrode, and (ii) a second configuration for performing a medical procedure using the plurality of functional electrodes.
12 . The method according to claim 9 , wherein determining that at least one of the plurality of functional electrodes is in physical contact with the wall tissue comprises determining that a measured impedance is lower than a prespecified impedance threshold.
13 . The method according to claim 12 , wherein the prespecified impedance threshold is measured while the reference electrode is in contact with blood in the cavity.