Granted Patent
B2
US 12,448,383 · App. 18/237,152 · Granted Oct 21, 2025
Compounds and methods for treatment of viral infections
Inventors:
Mark J. Bartlett (Castro Valley, CA); Daniel H. Byun (Foster City, CA); Yifan Deng (Milpitas, CA); Jennifer L. Cosman Ellis (Foster City, CA); Rao V. Kalla (Cupertino, CA); Richard L. Mackman (Millbrae, CA); Dustin S. Siegel (Half Moon Bay, CA); Xianhuang Zeng (Redwood City, CA)
Assignee:
Gilead Sciences, Inc.
View Patent ↗
Loading inventors, assignments & file history…
Abstract
Compounds and methods of using said compounds, singly or in combination with additional agents, and salts or pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
Claims (11)
1. A method of treating a coronavirus infection in a human in need thereof, wherein the method comprises administering to the human a compound of Formula:
or a pharmaceutically acceptable salt thereof.
2. The method of claim 1 , wherein the compound, or a pharmaceutically acceptable salt thereof, is administered to the human via oral administration.
3. The method of claim 1 , wherein the method comprises administering to the human at least one additional therapeutic or prophylactic agent.
4. The method of claim 1 , wherein the coronavirus infection is a zoonotic coronavirus infection.
5. The method of claim 1 , wherein the coronavirus infection is a SARS-COV-2 infection.
6. A method of treating a coronavirus infection in a human in need thereof, wherein the method comprises administering to the human a compound of Formula:
7. The method of claim 6 , wherein the compound is administered to the human via oral administration.
8. The method of claim 6 , wherein the method comprises administering to the human at least one additional therapeutic or prophylactic agent.
9. The method of claim 6 , wherein the coronavirus infection is a zoonotic coronavirus infection.
10. The method of claim 6 , wherein the coronavirus infection is a SARS-COV-2 infection.
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 14, 2023
From: BARTLETT, MARK J.; BYUN, DANIEL H.; DENG, YIFAN; COSMAN ELLIS, JENNIFER L.; KALLA, RAO V.; MACKMAN, RICHARD L.; SIEGEL, DUSTIN S.; ZENG, XIANHUANG
To: GILEAD SCIENCES, INC.
Reel/Frame 064908/0319 →
Continuity (7)
Provisional Application
63434993
· Dec 23, 2022
Provisional Application
63424083
· Nov 9, 2022
Provisional Application
63390421
· Jul 19, 2022
Provisional Application
63315769
· Mar 2, 2022
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